[HTML][HTML] Role of intra-and extracellular lipid signals in cancer stemness and potential therapeutic strategy
J Hu, L Zhang, W Chen, L Shen, J Jiang… - Frontiers in …, 2021 - frontiersin.org
Accumulating evidence showed that cancer stem cells (CSCs) play significant roles in
cancer initiation, resistance to therapy, recurrence and metastasis. Cancer stem cells …
cancer initiation, resistance to therapy, recurrence and metastasis. Cancer stem cells …
[HTML][HTML] Abnormal lipid synthesis as a therapeutic target for cancer stem cells
SY Wang, QC Hu, T Wu, J Xia, XA Tao… - World Journal of Stem …, 2022 - ncbi.nlm.nih.gov
Cancer stem cells (CSCs) comprise a subpopulation of cancer cells with stem cell
properties, which exhibit the characteristics of high tumorigenicity, self-renewal, and tumor …
properties, which exhibit the characteristics of high tumorigenicity, self-renewal, and tumor …
Role of aberrant lipid metabolism of cancer stem cells in cancer progression
J Zhou, J Zhao, C Su - Current Cancer Drug Targets, 2021 - ingentaconnect.com
Cancer stem cells (CSCs) represent a small population of cancer cells that are able to self-
renew and initiate tumors, which undergo epigenetic, epithelial-mesenchymal …
renew and initiate tumors, which undergo epigenetic, epithelial-mesenchymal …
Aberrant lipid metabolism as an emerging therapeutic strategy to target cancer stem cells
Emerging evidence in cancer metabolomics has identified reprogrammed metabolic
pathways to be a major hallmark of cancer, among which deregulated lipid metabolism is a …
pathways to be a major hallmark of cancer, among which deregulated lipid metabolism is a …
[HTML][HTML] Emerging role of lipid metabolism alterations in Cancer stem cells
M Yi, J Li, S Chen, J Cai, Y Ban, Q Peng, Y Zhou… - Journal of Experimental …, 2018 - Springer
Abstract Background Cancer stem cells (CSCs) or tumor-initiating cells (TICs) represent a
small population of cancer cells with self-renewal and tumor-initiating properties. Unlike the …
small population of cancer cells with self-renewal and tumor-initiating properties. Unlike the …
[HTML][HTML] Lipid metabolism alteration contributes to and maintains the properties of cancer stem cells
Lipids, the basic components of the cell membrane, execute fundamental roles in almost all
the cell activities including cell-cell recognition, signalling transduction and energy supplies …
the cell activities including cell-cell recognition, signalling transduction and energy supplies …
Lipid metabolism dynamics in cancer stem cells: potential targets for cancers
J Du, H Qin - Frontiers in Pharmacology, 2024 - frontiersin.org
Cancer stem cells (CSCs) represent a small subset of heterogeneous cells within tumors
that possess the ability to self-renew and initiate tumorigenesis. They serve as potential …
that possess the ability to self-renew and initiate tumorigenesis. They serve as potential …
[HTML][HTML] Bioactive lipids in cancer stem cells
Tumours are known to be a heterogeneous group of cells, which is why they are difficult to
eradicate. One possible cause for this is the existence of slow-cycling cancer stem cells …
eradicate. One possible cause for this is the existence of slow-cycling cancer stem cells …
Targeting autophagy and lipid metabolism in cancer stem cells
B Chakravarti, JA Siddiqui, RA Sinha, S Raza - Biochemical pharmacology, 2023 - Elsevier
Cancer stem cells (CSCs) are a subset of cancer cells with self-renewal ability and tumor
initiating properties. Unlike the other non-stem cancer cells, CSCs resist traditional therapy …
initiating properties. Unlike the other non-stem cancer cells, CSCs resist traditional therapy …
[HTML][HTML] Targeting Dysregulated Lipid Metabolism in Cancer with Pharmacological Inhibitors
A Gupta, D Das, R Taneja - Cancers, 2024 - mdpi.com
Simple Summary Lipid metabolism involves signalling pathways that control the uptake,
synthesis, and breakdown of lipid molecules. This highly controlled system is dysregulated …
synthesis, and breakdown of lipid molecules. This highly controlled system is dysregulated …