[HTML][HTML] Role of intra-and extracellular lipid signals in cancer stemness and potential therapeutic strategy

J Hu, L Zhang, W Chen, L Shen, J Jiang… - Frontiers in …, 2021 - frontiersin.org
Accumulating evidence showed that cancer stem cells (CSCs) play significant roles in
cancer initiation, resistance to therapy, recurrence and metastasis. Cancer stem cells …

[HTML][HTML] Abnormal lipid synthesis as a therapeutic target for cancer stem cells

SY Wang, QC Hu, T Wu, J Xia, XA Tao… - World Journal of Stem …, 2022 - ncbi.nlm.nih.gov
Cancer stem cells (CSCs) comprise a subpopulation of cancer cells with stem cell
properties, which exhibit the characteristics of high tumorigenicity, self-renewal, and tumor …

Role of aberrant lipid metabolism of cancer stem cells in cancer progression

J Zhou, J Zhao, C Su - Current Cancer Drug Targets, 2021 - ingentaconnect.com
Cancer stem cells (CSCs) represent a small population of cancer cells that are able to self-
renew and initiate tumors, which undergo epigenetic, epithelial-mesenchymal …

Aberrant lipid metabolism as an emerging therapeutic strategy to target cancer stem cells

M Visweswaran, F Arfuso, S Warrier… - Stem cells, 2020 - academic.oup.com
Emerging evidence in cancer metabolomics has identified reprogrammed metabolic
pathways to be a major hallmark of cancer, among which deregulated lipid metabolism is a …

[HTML][HTML] Emerging role of lipid metabolism alterations in Cancer stem cells

M Yi, J Li, S Chen, J Cai, Y Ban, Q Peng, Y Zhou… - Journal of Experimental …, 2018 - Springer
Abstract Background Cancer stem cells (CSCs) or tumor-initiating cells (TICs) represent a
small population of cancer cells with self-renewal and tumor-initiating properties. Unlike the …

[HTML][HTML] Lipid metabolism alteration contributes to and maintains the properties of cancer stem cells

H Li, Z Feng, ML He - Theranostics, 2020 - ncbi.nlm.nih.gov
Lipids, the basic components of the cell membrane, execute fundamental roles in almost all
the cell activities including cell-cell recognition, signalling transduction and energy supplies …

Lipid metabolism dynamics in cancer stem cells: potential targets for cancers

J Du, H Qin - Frontiers in Pharmacology, 2024 - frontiersin.org
Cancer stem cells (CSCs) represent a small subset of heterogeneous cells within tumors
that possess the ability to self-renew and initiate tumorigenesis. They serve as potential …

[HTML][HTML] Bioactive lipids in cancer stem cells

RR Begicevic, F Arfuso, M Falasca - World Journal of Stem Cells, 2019 - ncbi.nlm.nih.gov
Tumours are known to be a heterogeneous group of cells, which is why they are difficult to
eradicate. One possible cause for this is the existence of slow-cycling cancer stem cells …

Targeting autophagy and lipid metabolism in cancer stem cells

B Chakravarti, JA Siddiqui, RA Sinha, S Raza - Biochemical pharmacology, 2023 - Elsevier
Cancer stem cells (CSCs) are a subset of cancer cells with self-renewal ability and tumor
initiating properties. Unlike the other non-stem cancer cells, CSCs resist traditional therapy …

[HTML][HTML] Targeting Dysregulated Lipid Metabolism in Cancer with Pharmacological Inhibitors

A Gupta, D Das, R Taneja - Cancers, 2024 - mdpi.com
Simple Summary Lipid metabolism involves signalling pathways that control the uptake,
synthesis, and breakdown of lipid molecules. This highly controlled system is dysregulated …