Automated eukaryotic gene structure annotation using EVidenceModeler and the Program to Assemble Spliced Alignments

BJ Haas, SL Salzberg, W Zhu, M Pertea, JE Allen… - Genome biology, 2008 - Springer
EVidenceModeler (EVM) is presented as an automated eukaryotic gene structure annotation
tool that reports eukaryotic gene structures as a weighted consensus of all available …

Computational gene prediction using multiple sources of evidence

JE Allen, M Pertea, SL Salzberg - Genome research, 2004 - genome.cshlp.org
This article describes a computational method to construct gene models by using evidence
generated from a diverse set of sources, including those typical of a genome annotation …

Using native and syntenically mapped cDNA alignments to improve de novo gene finding

M Stanke, M Diekhans, R Baertsch, D Haussler - Bioinformatics, 2008 - academic.oup.com
Motivation: Computational annotation of protein coding genes in genomic DNA is a widely
used and essential tool for analyzing newly sequenced genomes. However, current …

MAKER: an easy-to-use annotation pipeline designed for emerging model organism genomes

BL Cantarel, I Korf, SMC Robb, G Parra… - Genome …, 2008 - genome.cshlp.org
We have developed a portable and easily configurable genome annotation pipeline called
MAKER. Its purpose is to allow investigators to independently annotate eukaryotic genomes …

Automatic annotation of eukaryotic genes, pseudogenes and promoters

V Solovyev, P Kosarev, I Seledsov, D Vorobyev - Genome biology, 2006 - Springer
Background The ENCODE gene prediction workshop (EGASP) has been organized to
evaluate how well state-of-the-art automatic gene finding methods are able to reproduce the …

JIGSAW: integration of multiple sources of evidence for gene prediction

JE Allen, SL Salzberg - Bioinformatics, 2005 - academic.oup.com
Motivation: Computational gene finding systems play an important role in finding new
human genes, although no systems are yet accurate enough to predict all or even most …

Structural and functional annotation of eukaryotic genomes with GenSAS

JL Humann, T Lee, S Ficklin, D Main - Gene prediction: methods and …, 2019 - Springer
Abstract The Genome Sequence Annotation Server (GenSAS, https://www. gensas. org) is a
secure, web-based genome annotation platform for structural and functional annotation, as …

Gene structure prediction from consensus spliced alignment of multiple ESTs matching the same genomic locus

V Brendel, L Xing, W Zhu - Bioinformatics, 2004 - academic.oup.com
Motivation: Accurate gene structure annotation is a challenging computational problem in
genomics. The best results are achieved with spliced alignment of full-length cDNAs or …

Annotating eukaryote genomes

S Lewis, M Ashburner, MG Reese - Current opinion in structural biology, 2000 - Elsevier
The Genome Annotation Assessment Project tested current methods of gene identification,
including a critical assessment of the accuracy of different methods. Two new databases …

Genome annotation in plants and fungi: EuGene as a model platform

S Foissac, J Gouzy, S Rombauts, C Mathé… - Current …, 2008 - ingentaconnect.com
In this era of whole genome sequencing, reliable genome annotations (identification of
functional regions) are the cornerstones for many subsequent analyses. Not only is careful …