Background Circulating biomarkers for lung damage are lacking. Lung epithelium-specific
DNA methylation patterns can potentially report the presence of lung-derived cell-free DNA …

As a noninvasive blood testing, the detection of cell‐free DNA (cfDNA) methylation in
plasma has raised an increasing interest due to diagnostic applications. Although …

Disease-specific alterations of the cell-free DNA methylation status are frequently found in
serum samples and are currently considered to be suitable biomarkers. Candidate markers …

Background Epigenetics changes have been shown to be affected by cigarette smoking.
Cigarette smoke (CS)-mediated DNA methylation can potentially affect several cellular and …

Background The objective of this study was to discover DNA methylation biomarkers for
detecting non-small lung cancer (NSCLC) in bronchial washings and understanding the …

Alteration of DNA methylation patterns at the 5′ position of cytosines, in the context of CpG
dinucleotides, is one of the most promising epigenetic biomarkers for many biomedical …

Background Lung cancer remains the leading cause of cancer mortality worldwide. Early
detection of lung cancer helps improve treatment and survival. Numerous aberrant DNA …

Lung cancer is the number one cancer killer in the United States. This disease is clinically
divided into two sub-types, small cell lung cancer,(10–15% of lung cancer cases), and non …

Background: DNA methylation markers have been associated with lung cancer risk and may
identify aetiologically relevant genomic regions, or alternatively, be markers of disease risk …

Background. Lung cancer is still the deadliest cancer in the world, but early diagnosis
cannot be achieved because of the limitations of diagnostic methods. DNA methylation has …