Maintenance of fluid and electrolyte homeostasis is critical for normal neuromuscular
function. Bartter's syndrome is an autosomal recessive disease characterized by diverse …

Inherited hypokalaemic alkalosis with low blood pressure can be divided into two groups—
Gitelman's syndrome, featuring hypocalciuria, hypomagnesaemia and milder clinical …

Hypokalemic alkalosis with low blood pressure can be caused by a number of medications
or alternatively as an autosomal recessive genetic trait. Molecular genetic approaches to this …

Inherited hypokalemic metabolic alkalosis, or Bartter syndrome, comprises several closely
related disorders of renal tubular electrolyte transport. Recent advances in the field of …

Familial hypokalemic, hypochloremic metabolic alkalosis, or Bartter syndrome, is not a
single disorder but rather a set of closely related disorders. These Bartter-like syndromes …

Abstract Analysis of patients with inherited hypokalaemic alkalosis resulting from salt–
wasting has proved fertile ground for identification of essential elements of renal salt …

Inherited renal tubular disorders associated with hypokalemic alkalosis (Bartter-like
syndromes) can be subdivided into at least three clinical phenotypes:(i) the hypocalciuric …

It is now evident that the term Bartter syndrome does not represent a unique entity but
encompasses a variety of disorders of renal electrolyte transport. Application of molecular …

Elucidation of the gene defects responsible for many disorders of renal fluid and electrolyte
homeostasis has provided new insights into normal and abnormal physiology. Identifying …

Mutations in the gene encoding the thiazide-sensitive Na+-Cl− cotransporter (NCC) of the
distal convoluted tubule cause Gitelman's syndrome, an inherited hypokalemic alkalosis …