Metabolic engineering of Escherichia coli for the biosynthesis of various phenylpropanoid derivatives
S Wang, S Zhang, A Xiao, M Rasmussen… - Metabolic …, 2015 - Elsevier
Plants produce a variety of natural products with promising biological activities, such as the
phenylpropanoids resveratrol and curcumin. While these molecules are naturally assembled …
phenylpropanoids resveratrol and curcumin. While these molecules are naturally assembled …
Biosynthesis of plant-specific phenylpropanoids by construction of an artificial biosynthetic pathway in Escherichia coli
O Choi, CZ Wu, SY Kang, JS Ahn… - Journal of Industrial …, 2011 - academic.oup.com
Biological synthesis of plant secondary metabolites has attracted increasing attention due to
their proven or assumed beneficial properties and health-promoting effects …
their proven or assumed beneficial properties and health-promoting effects …
Combinatorial biosynthesis of non-bacterial and unnatural flavonoids, stilbenoids and curcuminoids by microorganisms
S Horinouchi - The Journal of antibiotics, 2008 - nature.com
One of the approaches of combinatorial biosynthesis is combining genes from different
organisms and designing a new set of gene clusters to produce bioactive compounds …
organisms and designing a new set of gene clusters to produce bioactive compounds …
Metabolic engineering of microorganisms for the production of natural compounds
Natural products have been attracting much interest around the world for their diverse
applications, especially in drug and food industries. Plants have been a major source of …
applications, especially in drug and food industries. Plants have been a major source of …
New frontiers: harnessing pivotal advances in microbial engineering for the biosynthesis of plant-derived terpenoids
MS Belcher, J Mahinthakumar, JD Keasling - Current opinion in …, 2020 - Elsevier
Highlights•Terpenoids are a vast and diverse class of compounds with applications in both
the industrial and human health spaces.•Computational biology and gene discovery enable …
the industrial and human health spaces.•Computational biology and gene discovery enable …
Engineered biosynthesis of natural products in heterologous hosts
Natural products produced by microorganisms and plants are a major resource of
antibacterial and anticancer drugs as well as industrially useful compounds. However, the …
antibacterial and anticancer drugs as well as industrially useful compounds. However, the …
Combinatorial biosynthesis of plant medicinal polyketides by microorganisms
S Horinouchi - Current opinion in chemical biology, 2009 - Elsevier
Combinatorial biosynthesis includes an approach in which genes from different organisms
are assembled to design and construct an artificial gene cluster for production of bioactive …
are assembled to design and construct an artificial gene cluster for production of bioactive …
Current and emerging approaches for natural product biosynthesis in microbial cells
KT Watts, BN Mijts… - Advanced Synthesis & …, 2005 - Wiley Online Library
Microorganisms and plants synthesize a tremendous diversity of chemical compounds. For
centuries, these compounds have been used as medicines, foods and other useful …
centuries, these compounds have been used as medicines, foods and other useful …
Metabolic engineering of Escherichia coli for natural product biosynthesis
Natural products are widely employed in our daily lives as food additives, pharmaceuticals,
nutraceuticals, and cosmetic ingredients, among others. However, their supply has often …
nutraceuticals, and cosmetic ingredients, among others. However, their supply has often …
Improvement of catechin production in Escherichia coli through combinatorial metabolic engineering
Reconstruction of highly efficient biosynthesis pathways is essential for the production of
valuable plant secondary metabolites in recombinant microorganisms. In order to improve …
valuable plant secondary metabolites in recombinant microorganisms. In order to improve …