Berberine as a natural modulator of inflammatory signaling pathways in the immune system: Focus on NF‐κB, JAK/STAT, and MAPK signaling pathways
SM Haftcheshmeh, M Abedi… - Phytotherapy …, 2022 - Wiley Online Library
Three main inflammatory signaling pathways include nuclear factor‐κB (NF‐κB), Janus
kinases/Signal transducer and activator of transcriptions (JAKs/STATs), and mitogen …
kinases/Signal transducer and activator of transcriptions (JAKs/STATs), and mitogen …
Berberine suppresses LPS-induced inflammation through modulating Sirt1/NF-κB signaling pathway in RAW264. 7 cells
H Zhang, Y Shan, Y Wu, C Xu, X Yu, J Zhao… - International …, 2017 - Elsevier
Chronic inflammation is a major contributing factor in the pathogenesis of many diseases.
Natural product berberine (BBR) exhibits potent anti-inflammatory effect in vitro and in vivo …
Natural product berberine (BBR) exhibits potent anti-inflammatory effect in vitro and in vivo …
Immunological axis of berberine in managing inflammation underlying chronic respiratory inflammatory diseases
XN Tew, NJX Lau, DK Chellappan… - Chemico-biological …, 2020 - Elsevier
Inflammatory responses play a remarkable role in the mechanisms of acute and chronic
respiratory diseases such as chronic obstructive pulmonary disease (COPD), asthma …
respiratory diseases such as chronic obstructive pulmonary disease (COPD), asthma …
Berberine attenuates arthritis in adjuvant-induced arthritic rats associated with regulating polarization of macrophages through AMPK/NF-кB pathway
J Zhou, Y Yu, X Yang, Y Wang, Y Song, Q Wang… - European Journal of …, 2019 - Elsevier
Berberine (BBR) is a traditional folk medicine with excellent anti-inflammatory properties.
This study aimed to investigate the anti-arthritic effects of BBR in adjuvant arthritis (AA) in …
This study aimed to investigate the anti-arthritic effects of BBR in adjuvant arthritis (AA) in …
[HTML][HTML] Inhibitory effects of berberine on proinflammatory M1 macrophage polarization through interfering with the interaction between TLR4 and MyD88
J Gong, J Li, H Dong, G Chen, X Qin, M Hu… - … and alternative medicine, 2019 - Springer
Backgrounds Inflammation is recognized as the key pathological mechanism of type 2
diabetes. The hypoglyceamic effects of berberine (BBR) are related to the inhibition of the …
diabetes. The hypoglyceamic effects of berberine (BBR) are related to the inhibition of the …
Anti‐inflammatory and immune‐modulatory impacts of berberine on activation of autoreactive T cells in autoimmune inflammation
SM Ehteshamfar, M Akhbari, JT Afshari… - Journal of cellular …, 2020 - Wiley Online Library
Autoreactive inflammatory CD4+ T cells, such as T helper (Th) 1 and Th17 subtypes, have
been found to associate with the pathogenesis of autoimmune disorders. On the other hand …
been found to associate with the pathogenesis of autoimmune disorders. On the other hand …
Comparison of anti-inflammatory effects of berberine, and its natural oxidative and reduced derivatives from Rhizoma Coptidis in vitro and in vivo
CL Li, LH Tan, YF Wang, CD Luo, HB Chen, Q Lu… - Phytomedicine, 2019 - Elsevier
Background Berberine (BBR) is the most abundant and major active constituent of Rhizoma
Coptidis (RC), which has been widely used to treat inflammatory diseases in traditional …
Coptidis (RC), which has been widely used to treat inflammatory diseases in traditional …
Berberine suppresses proinflammatory responses through AMPK activation in macrophages
HW Jeong, KC Hsu, JW Lee, M Ham… - American Journal …, 2009 - journals.physiology.org
Berberine (BBR) has been shown to improve several metabolic disorders, such as obesity,
type 2 diabetes, and dyslipidemia, by stimulating AMP-activated protein kinase (AMPK) …
type 2 diabetes, and dyslipidemia, by stimulating AMP-activated protein kinase (AMPK) …
Berberine suppresses inflammatory agents-induced interleukin-1β and tumor necrosis factor-α productions via the inhibition of IκB degradation in human lung cells
CH Lee, JC Chen, CY Hsiang, SL Wu, HC Wu… - Pharmacological …, 2007 - Elsevier
Pulmonary inflammation is a characteristic of many lung diseases. Increased levels of pro-
inflammatory cytokines, such as interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) …
inflammatory cytokines, such as interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) …
[HTML][HTML] Berberine a traditional Chinese drug repurposing: Its actions in inflammation-associated ulcerative colitis and cancer therapy
C Zhu, K Li, XX Peng, TJ Yao, ZY Wang, P Hu… - Frontiers in …, 2022 - frontiersin.org
Berberine (BBR), an isoquinoline alkaloid extracted from Coptidis Rhizoma, has a long
history of treating dysentery in the clinic. Over the past two decades, the polytrophic …
history of treating dysentery in the clinic. Over the past two decades, the polytrophic …