[HTML][HTML] A pilot genome-wide association study identifies potential metabolic pathways involved in tinnitus

A Gilles, G Van Camp, P Van de Heyning… - Frontiers in …, 2017 - frontiersin.org
Tinnitus, the perception of an auditory phantom sound in the form of ringing, buzzing,
roaring, or hissing in the absence of an external sound source, is perceived by~ 15% of the …

[HTML][HTML] Genetic predisposition to tinnitus in the UK Biobank population

ME Urbanek, J Zuo - Scientific reports, 2021 - nature.com
Tinnitus, the phantom perception of noise originating from the inner ear, has been reported
by 15% of the world's population, with many patients reporting major deficits to cognition and …

[HTML][HTML] A genome-wide association study of tinnitus reveals shared genetic links to neuropsychiatric disorders

IS Bhatt, N Wilson, R Dias, A Torkamani - Scientific reports, 2022 - nature.com
Tinnitus, a phantom perception of sound in the absence of any external sound source, is a
prevalent health condition often accompanied by psychiatric comorbidities. Recent genome …

[HTML][HTML] Genetics of tinnitus: still in its infancy

B Vona, I Nanda, W Shehata-Dieler… - Frontiers in neuroscience, 2017 - frontiersin.org
Tinnitus is the perception of a phantom sound that affects between 10 and 15% of the
general population. Despite this considerable prevalence, treatments for tinnitus are …

[HTML][HTML] Genetics of tinnitus: time to biobank phantom sounds

CR Cederroth, AK Kähler, PF Sullivan… - Frontiers in …, 2017 - frontiersin.org
Tinnitus is a common phantom sensation resulting most often from sensory deprivation, and
for which little knowledge on the molecular mechanisms exists. While the existing evidence …

[HTML][HTML] Genetics of tinnitus: an emerging area for molecular diagnosis and drug development

JA Lopez-Escamez, T Bibas, RFF Cima… - Frontiers in …, 2016 - frontiersin.org
Subjective tinnitus is the perception of sound in the absence of external or bodily-generated
sounds. Chronic tinnitus is a highly prevalent condition affecting over 70 million people in …

Novel risk loci in tinnitus and causal inference with neuropsychiatric disorders among adults of European ancestry

RE Clifford, AX Maihofer, MB Stein… - … –Head & Neck …, 2020 - jamanetwork.com
Importance Tinnitus affects at least 16 million US adults, but its pathophysiology is
complicated, and treatment options remain limited. A heritable component has been …

[HTML][HTML] Genetic architecture distinguishes tinnitus from hearing loss

RE Clifford, AX Maihofer, C Chatzinakos… - Nature …, 2024 - nature.com
Tinnitus is a heritable, highly prevalent auditory disorder treated by multiple medical
specialties. Previous GWAS indicated high genetic correlations between tinnitus and …

Understanding factors that cause tinnitus: A mendelian randomization study in the UK Biobank

M Cresswell, F Casanova, RN Beaumont… - Ear and …, 2022 - journals.lww.com
Objectives: To investigate the causal role of established risk factors and associated
conditions to tinnitus and tinnitus severity in the UK Biobank. Design: The prospective cohort …

[HTML][HTML] Genome-wide association study suggests that variation at the RCOR1 locus is associated with tinnitus in UK Biobank

HRR Wells, FNZ Abidin, MB Freidin, FMK Williams… - Scientific Reports, 2021 - nature.com
Tinnitus is a prevalent condition in which perception of sound occurs without an external
stimulus. It is often associated with pre-existing hearing loss or noise-induced damage to the …