Rationale: Nasal polyps (NPs) are characterized by intense edema or formation of
pseudocysts filled with plasma proteins, mainly albumin. However, the mechanisms …

Background Profound edema or formation of a pseudocyst containing plasma proteins is a
prominent characteristic of nasal polyps (NP). However, the mechanisms underlying NP …

Chronic rhinosinusitis (CRS) is one of the most common chronic diseases worldwide. It is a
heterogeneous disease, and geographical or ethnic differences in inflammatory pattern in …

Background Activation of the coagulation system with an increase in thrombin generation is
involved in the pathogenesis of tissue remodeling in chronic rhinosinusitis (CRS). Tissue …

Chronic rhinosinusitis (CRS) is one of the most common chronic diseases in adults and
severely affects quality of life in patients. Although various etiologic and pathogenic …

Background Thrombin, the effector enzyme of the coagulation system, has been reported to
promote inflammatory responses in nasal diseases through its protease-activated receptors …

Background The exact etiologic mechanisms leading to the formation of nasal polyps have
remained largely obscure. A key phenomenon of this specific type of chronic inflammatory …

Background The coagulation pathway has been previously implicated in the
etiopathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP) through analysis of …

Background Staphylococcus aureus is a common bacterial pathogen associated with
chronic rhinosinusitis with/without nasal polyps (CRSw/sNP). We investigated the effect of S …

Abstract Objectives/Hypothesis: Chronic hyperplastic sinusitis (CHS) with nasal polyps (NP)
is characterized by extensive mucosal thickening, goblet cell hyperplasia, and subepithelial …