Acetaminophen hepatotoxicity
AM Larson - Clinics in liver disease, 2007 - Elsevier
Acetaminophen is a commonly used antipyretic and analgesic agent. It is safe when taken at
therapeutic doses; however, overdose can lead to serious and even fatal hepatotoxicity. The …
therapeutic doses; however, overdose can lead to serious and even fatal hepatotoxicity. The …
Acetaminophen hepatotoxicity and acute liver failure
LJ Chun, MJ Tong, RW Busuttil… - Journal of clinical …, 2009 - journals.lww.com
Acetaminophen-induced hepatotoxicity is a common consequence of acetaminophen
overdose and may lead to acute liver failure (ALF). Currently acetaminophen is the most …
overdose and may lead to acute liver failure (ALF). Currently acetaminophen is the most …
Acetaminophen hepatotoxicity: An update
CJ McClain, S Price, S Barve, R Devalarja… - Current …, 1999 - Springer
Acetaminophen is a widely used nonprescription analgesic and antipyretic agent. It is also a
dose-related hepatotoxin that can cause fulminant liver failure when taken in massive …
dose-related hepatotoxin that can cause fulminant liver failure when taken in massive …
[HTML][HTML] Acetaminophen-induced hepatotoxicity: a comprehensive update
E Yoon, A Babar, M Choudhary, M Kutner… - Journal of clinical and …, 2016 - ncbi.nlm.nih.gov
Hepatic injury and subsequent hepatic failure due to both intentional and non-intentional
overdose of acetaminophen (APAP) has affected patients for decades, and involves the …
overdose of acetaminophen (APAP) has affected patients for decades, and involves the …
Acetaminophen hepatotoxicity: an updated review
EM Lancaster, JR Hiatt, A Zarrinpar - Archives of toxicology, 2015 - Springer
As the most common cause of acute liver failure (ALF) in the USA and UK, acetaminophen-
induced hepatotoxicity remains a significant public health concern and common indication …
induced hepatotoxicity remains a significant public health concern and common indication …
Evaluation and treatment of acetaminophen toxicity
ES Fisher, SC Curry - Advances in pharmacology, 2019 - Elsevier
A review of the typical clinical course, diagnosis and treatment of acetaminophen toxicity is
provided. For an acute overdose, most adults must ingest about 12 g or more …
provided. For an acute overdose, most adults must ingest about 12 g or more …
A 7-year experience of severe acetaminophen-induced hepatotoxicity (1987–1993)
AJ Makin, J Wendon, R Williams - Gastroenterology, 1995 - Elsevier
Background & Aims: Five hundred sixty patients admitted between January 1, 1987, and
December 31, 1993, with severe acetaminophen-induced hepatotoxicity were studied. The …
December 31, 1993, with severe acetaminophen-induced hepatotoxicity were studied. The …
Acetaminophen hepatotoxicity
M Black - Gastroenterology, 1980 - Elsevier
Over the past five or more years, laboratory and clinical investigations aimed at elucidating
the pathogenesis of acetaminophen-induced liver-cell necrosis have achieved a striking …
the pathogenesis of acetaminophen-induced liver-cell necrosis have achieved a striking …
Severe hepatotoxicity after therapeutic doses of acetaminophen
O Moling, E Cairon, G Rimenti, F Rizza, R Pristerá… - Clinical …, 2006 - Elsevier
Background: Acetaminophen overdose is a frequent cause of acute liver failure. Controversy
exists over the rare association of severe hepatotoxicity or acute liver failure with therapeutic …
exists over the rare association of severe hepatotoxicity or acute liver failure with therapeutic …
The therapeutic use of acetaminophen in patients with liver disease
GD Benson, RS Koff, KG Tolman - American journal of …, 2005 - journals.lww.com
Acetaminophen has been used safely and effectively for many years to manage pain and/or
fever in patients of all ages. It is commonly recommended as first-line therapy for a variety of …
fever in patients of all ages. It is commonly recommended as first-line therapy for a variety of …