SARS-CoV-2 infection leads to acute infection with dynamic cellular and inflammatory flux in the lung that varies across nonhuman primate species
There are no known cures or vaccines for COVID-19, the defining pandemic of this era.
Animal models are essential to fast track new interventions and nonhuman primate (NHP) …
Animal models are essential to fast track new interventions and nonhuman primate (NHP) …
Responses to acute infection with SARS-CoV-2 in the lungs of rhesus macaques, baboons and marmosets
Non-human primate models will expedite therapeutics and vaccines for coronavirus disease
2019 (COVID-19) to clinical trials. Here, we compare acute severe acute respiratory …
2019 (COVID-19) to clinical trials. Here, we compare acute severe acute respiratory …
[HTML][HTML] SARS-CoV-2 infection dynamics in lungs of African green monkeys
E Speranza, BN Williamson, F Feldmann… - bioRxiv, 2020 - ncbi.nlm.nih.gov
Detailed knowledge about the dynamics of SARS-CoV-2 infection is important for unraveling
the viral and host factors that contribute to COVID-19 pathogenesis. Old-World nonhuman …
the viral and host factors that contribute to COVID-19 pathogenesis. Old-World nonhuman …
Cellular events of acute, resolving or progressive COVID-19 in SARS-CoV-2 infected non-human primates
MD Fahlberg, RV Blair, LA Doyle-Meyers… - Nature …, 2020 - nature.com
Understanding SARS-CoV-2 associated immune pathology is crucial to develop pan-
effective vaccines and treatments. Here we investigate the immune events from the acute …
effective vaccines and treatments. Here we investigate the immune events from the acute …
The pigtail macaque (Macaca nemestrina) model of COVID-19 reproduces diverse clinical outcomes and reveals new and complex signatures of disease
A Melton, LA Doyle-Meyers, RV Blair, C Midkiff… - PLoS …, 2021 - journals.plos.org
The novel coronavirus SARS-CoV-2, the causative agent of COVID-19 disease, has killed
over five million people worldwide as of December 2021 with infections rising again due to …
over five million people worldwide as of December 2021 with infections rising again due to …
Exposure modality influences viral kinetics but not respiratory outcome of COVID-19 in multiple nonhuman primate species
AC Fears, BJ Beddingfield, NR Chirichella… - PLoS …, 2022 - journals.plos.org
The novel coronavirus SARS-CoV-2 emerged in late 2019, rapidly reached pandemic
status, and has maintained global ubiquity through the emergence of variants of concern …
status, and has maintained global ubiquity through the emergence of variants of concern …
Single-cell landscape of lungs reveals key role of neutrophil-mediated immunopathology during lethal SARS-CoV-2 infection
XS Zheng, Q Wang, J Min, XR Shen, Q Li… - Journal of …, 2022 - Am Soc Microbiol
Due to the limitation of human studies with respect to individual difference or the
accessibility of fresh tissue samples, how severe acute respiratory syndrome coronavirus 2 …
accessibility of fresh tissue samples, how severe acute respiratory syndrome coronavirus 2 …
Comparison of rhesus and cynomolgus macaques as an infection model for COVID-19
FJ Salguero, AD White, GS Slack… - Nature …, 2021 - nature.com
A novel coronavirus, SARS-CoV-2, has been identified as the causative agent of the current
COVID-19 pandemic. Animal models, and in particular non-human primates, are essential to …
COVID-19 pandemic. Animal models, and in particular non-human primates, are essential to …
[PDF][PDF] Comparison of SARS-CoV-2 infection in two non-human primate species: Rhesus and Cynomolgus macaques
KP Böszörményi, MA Stammes, ZC Fagrouch… - BioRxiv, 2020 - researchgate.net
SARS-CoV-2 is a coronavirus that sparked the current COVID-19 pandemic. To stop the 29
shattering effect of COVID-19, effective and safe vaccines, and antiviral therapies are …
shattering effect of COVID-19, effective and safe vaccines, and antiviral therapies are …
Analysis of respiratory and systemic immune responses in COVID-19 reveals mechanisms of disease pathogenesis
Immune responses to respiratory viruses like SARS-CoV-2 originate and function in the
lung, yet assessments of human immunity are often limited to blood. Here, we conducted …
lung, yet assessments of human immunity are often limited to blood. Here, we conducted …
相关搜索
- acute infection sars cov
- primate species sars cov
- primate species acute infection
- cellular events sars cov
- disease pathology sars cov
- rhesus macaques sars cov
- primate species covid 19
- covid 19 sars cov
- primate species viral kinetics
- rhesus macaques acute infection
- primate species exposure modality
- comprehensive analysis sars cov
- infection dynamics sars cov