Hematopoietic mosaic loss of Y chromosome (mLOY) is associated with increased risk of
mortality and age-related diseases in men, but the causal and mechanistic relationships …

Recent discoveries have shown that harboring cells without the Y chromosome in the
peripheral blood is associated with increased risk for all-cause mortality and disease such …

Mosaic loss of chromosome Y (LOY) in circulating white blood cells is the most common
form of clonal mosaicism,,,–, yet our knowledge of the causes and consequences of this is …

Mosaic loss of chromosome Y (mLOY) is frequently observed in the leukocytes of ageing
men. However, the genetic architecture and biological mechanisms underlying mLOY are …

The Y chromosome is frequently lost in hematopoietic cells, which represents the most
common somatic alteration in men. However, the mechanisms that regulate mosaic loss of …

Mosaic loss of Y chromosome (mLOY) is the most frequently detected somatic copy number
alteration in leukocytes of men. In this study, we investigate blood cell counts as a potential …

Mosaic loss of the Y chromosome (mLOY) is the most commonly reported large structural
somatic event. Previous studies have indicated age and cigarette smoking increase the risk …

To the Editor—Recent studies have found associations between loss of chromosome Y
(LOY) in leukocytes and an increased risk for all-cause mortality1 as well as various …

Mosaic loss of the Y chromosome (mLOY) in peripheral leukocytes is a somatic event in
which a fraction of leukocytes have lost the entire Y chromosome. The frequency of mLOY …

Mosaic loss of chromosome Y (mLOY) in blood cells is one of the most frequent
chromosome alterations in adult males. It is strongly associated with clonal hematopoiesis …