Correlation of camptothecin-producing ability and phylogenetic relationship in the genus Ophiorrhiza
V Viraporn, M Yamazaki, K Saito… - Planta …, 2011 - thieme-connect.com
Camptothecin (CPT) is an essential precursor of semisynthetic chemotherapeutic agents for
cancers throughout the world. In spite of the rapid growth of market demand, CPT raw …
cancers throughout the world. In spite of the rapid growth of market demand, CPT raw …
Divergent camptothecin biosynthetic pathway in Ophiorrhiza pumila
M Yang, Q Wang, Y Liu, X Hao, C Wang, Y Liang… - BMC biology, 2021 - Springer
Background The anticancer drug camptothecin (CPT), first isolated from Camptotheca
acuminata, was subsequently discovered in unrelated plants, including Ophiorrhiza pumila …
acuminata, was subsequently discovered in unrelated plants, including Ophiorrhiza pumila …
Ophiorrhiza, a promising herbaceous source of the anticancer compound camptothecin
G Krishnakumar, KP Dintu, SC Varghese… - Plant Science …, 2020 - horizonepublishing.com
Camptothecin is an important source for the synthesis of some of the major anti-cancer
agents such as irinotecan and topotecan. Traditional source of camptothecin are …
agents such as irinotecan and topotecan. Traditional source of camptothecin are …
Biotechnology for micropropagation and camptothecin production in Ophiorrhiza sp.
DK Pandey, M Konjengbam, M Ghorai… - Applied Microbiology …, 2022 - Springer
Camptothecin (CPT) is a monoterpenoid-alkaloid, an anticancer compound from plant. Ever
since its discovery in 1996 from the bark of Camptotheca acuminata, various researches …
since its discovery in 1996 from the bark of Camptotheca acuminata, various researches …
Biotechnology of camptothecin production in Nothapodytes nimmoniana, Ophiorrhiza sp. and Camptotheca acuminata
Cancer is probably the deadliest human disease in recent years. In the past few years, rapid
clinical progress has been made in the field of anticancer drug development. Plant …
clinical progress has been made in the field of anticancer drug development. Plant …
Search for camptothecin-yielding Ophiorrhiza species from southern Western Ghats in India: a HPTLC-densitometry study
R Rajan, SC Varghese, R Kurup… - Industrial Crops and …, 2013 - Elsevier
Camptothecin (CPT) content in 44 accessions belonging to nine Ophiorrhiza species and
three varieties collected from their natural habitats in the Kerala region of Western Ghats …
three varieties collected from their natural habitats in the Kerala region of Western Ghats …
Camptothecin production by in vitro cultures of Ophiorrhiza liukiuensis and O. kuroiwai
T Asano, I Watase, H Sudo, M KITAJIMA… - Plant …, 2004 - jstage.jst.go.jp
Camptothecin derived compounds are widely used for clinical treatment of human cancer.
They are synthesized from natural camptothecin, which is obtained by extraction from intact …
They are synthesized from natural camptothecin, which is obtained by extraction from intact …
Suppression of camptothecin biosynthetic genes results in metabolic modification of secondary products in hairy roots of Ophiorrhiza pumila
T Asano, K Kobayashi, E Kashihara, H Sudo, R Sasaki… - Phytochemistry, 2013 - Elsevier
Camptothecin is a monoterpenoid indole alkaloid that exhibits anti-tumor activity. In
Ophiorrhiza pumila, production of camptothecin and its related alkaloids was high in the …
Ophiorrhiza pumila, production of camptothecin and its related alkaloids was high in the …
HPTLC-based quantification of camptothecin in Ophiorrhiza species of the southern Western Ghats in India
R Rajan, SC Varghese, R Kurup… - Cogent …, 2016 - Taylor & Francis
Camptothecin (CPT), a modified monoterpene indole alkaloid, is a potential anticancer drug,
and due to high demand, search for its new plant-based sources is a priority. Genus …
and due to high demand, search for its new plant-based sources is a priority. Genus …
Tissue culture studies and estimation of camptothecin from Ophiorrhiza prostrata D. Don
K Gopalakrishnan, S Krishnan… - Indian journal of plant …, 2018 - Springer
Camptothecin is an important molecule in the synthesis of some of major anticancer agents
such as irinotecan and topotecan. Traditional sources of camptothecin are mainly woody …
such as irinotecan and topotecan. Traditional sources of camptothecin are mainly woody …