Human CD1d–glycolipid tetramers generated by in vitro oxidative refolding chromatography
A Karadimitris, S Gadola… - Proceedings of the …, 2001 - National Acad Sciences
CD1 molecules are specialized in presenting lipids to T lymphocytes, but identification and
isolation of CD1-restricted lipidspecific T cells has been hampered by the lack of reliable …
isolation of CD1-restricted lipidspecific T cells has been hampered by the lack of reliable …
CD1 tetramers: a powerful tool for the analysis of glycolipid-reactive T cells
S Sidobre, M Kronenberg - Journal of immunological methods, 2002 - Elsevier
CD1 proteins constitute a third class of antigen-presenting molecules. They bind lipids rather
than peptides, and the T cells reactive to lipids presented by CD1 have been implicated in …
than peptides, and the T cells reactive to lipids presented by CD1 have been implicated in …
Discovery of deoxyceramides and diacylglycerols as CD1b scaffold lipids among diverse groove-blocking lipids of the human CD1 system
S Huang, TY Cheng, DC Young… - Proceedings of the …, 2011 - National Acad Sciences
Unlike the dominant role of one class II invariant chain peptide (CLIP) in blocking MHC class
II, comparative lipidomics analysis shows that human cluster of differentiation (CD) proteins …
II, comparative lipidomics analysis shows that human cluster of differentiation (CD) proteins …
Natural lipid ligands associated with human CD1d targeted to different subcellular compartments
CD1d is an MHC class I-like membrane glycoprotein that presents lipid Ags to NKT cells.
Despite intensive biochemical, genetic, and structural studies, the endogenous lipids …
Despite intensive biochemical, genetic, and structural studies, the endogenous lipids …
Functional CD1a is stabilized by exogenous lipids
V Manolova, M Kistowska, S Paoletti… - European journal of …, 2006 - Wiley Online Library
Self‐glycosphingolipids bind to surface CD1 molecules and are readily displaced by other
CD1 ligands. This capacity to exchange antigens at the cell surface is not common to other …
CD1 ligands. This capacity to exchange antigens at the cell surface is not common to other …
CD1d antigen presentation: treats for NKT cells
DI Godfrey, J McCluskey, J Rossjohn - Nature immunology, 2005 - nature.com
Structural studies of CD1d presentation of α-galactosylceramide have shown that the lipid
component fits snugly in the cleft, whereas the galactosyl head group protrudes upward, with …
component fits snugly in the cleft, whereas the galactosyl head group protrudes upward, with …
In vivo identification of glycolipid antigen–specific T cells using fluorescent CD1d tetramers
K Benlagha, A Weiss, A Beavis, L Teyton… - The Journal of …, 2000 - rupress.org
The CD1 family of major histocompatibility complex (MHC)-like molecules specializes in
presenting lipid and glycolipid antigens to α/β T lymphocytes, but little is known about the …
presenting lipid and glycolipid antigens to α/β T lymphocytes, but little is known about the …
Crystal structure of human CD1e reveals a groove suited for lipid-exchange processes
LF Garcia-Alles, G Giacometti… - Proceedings of the …, 2011 - National Acad Sciences
CD1e is the only human CD1 protein existing in soluble form in the late endosomes of
dendritic cells, where it facilitates the processing of glycolipid antigens that are ultimately …
dendritic cells, where it facilitates the processing of glycolipid antigens that are ultimately …
Antigen presentation by CD1 molecules and the generation of lipid-specific T cell immunity
G Bricard, SA Porcelli - Cellular and molecular life sciences, 2007 - Springer
It is now well demonstrated that the repertoire of T cells includes not only cells that recognize
specific MHC-presented peptide antigens, but also cells that recognize specific self and …
specific MHC-presented peptide antigens, but also cells that recognize specific self and …
Presentation of the same glycolipid by different CD1 molecules
A Shamshiev, HJ Gober, A Donda, Z Mazorra… - The Journal of …, 2002 - rupress.org
Five CD1 molecules are expressed in humans and it is unclear whether they have
specialized or redundant functions. We found that sulfatide is a promiscuous CD1-binding …
specialized or redundant functions. We found that sulfatide is a promiscuous CD1-binding …