By constructing ternary phase diagrams it was possible to identify two self-microemulsifying
drug delivery systems (SMEDDS) containing either medium chain triglycerides (MC …

The bioavailability of seocalcitol from two lipid-based formulations and a propylene glycol
(PG) solution was studied in minipigs in the fasted and fed state. The lipid-based …

Simulated intestinal media (SIM) containing bile salt (BS) and phospholipids (PL) with and
without medium chain lipolytic products (MC-LP) or long chain lipolytic products (LC-LP) …

The oral delivery of hydrophobic drug presents a major challenge because of the low
aqueous solubility of such compounds. Self-emulsifying/microemulsifying drug delivery …

The main purpose of this work is to prepare self-microemulsifying drug delivery system
(SMEDDS) for oral bioavailability enhancement of a poorly water soluble drug, simvastatin …

The objective of the study was to develop a self-microemulsifying drug delivery system
(SMEDDS), also known as microemulsion preconcentrate, for oral delivery of five poorly …

To improve the dissolution and oral bioavailability (BA) of atorvastatin calcium (ATV), we
previously introduced an optimized self-microemulsifying drug delivery system (SMEDDS) …

The aims of this study were to formulate a self-microemulsifying drug delivery system
(SMEDDS) by a rational formulation approach using mixture experimental design and to …

Sažetak Self-microemulsifying drug delivery system (SMEDDS) of lovastatin was aimed at
overcoming the problems of poor solubility and bioavailability. The formulation strategy …

In order to gain a better understanding of the reasons of successful self-microemulsifying
drug delivery systems (SMEDDS) formulation, ten poorly water-soluble drugs, exhibiting …