Exsanguination is responsible for 30% to 40% of trauma-related deaths. 1, 2 Most of these
fatalities occur in the prehospital setting. According to standard coagulation tests (SCTs) …

BACKGROUND Rapid assessment and treatment of coagulopathy reduces postinjury
morbidity and mortality. Although thrombelastography (TEG) may be more accurate and …

Purpose Over the last decade, the pivotal role of trauma-induced coagulopathy has been
described and principal drivers have been identified. We hypothesized that the increased …

Background: Hemorrhage is a leading cause of death in trauma patients and coagulopathy
is a significant contributor. Although the exact mechanisms of trauma-associated …

INTRODUCTION: Progressive postinjury coagulopathy has become the fundamental
rationale for damage control surgery, and the decision to abort operative intervention must …

The concept of impaired coagulation following injury has been the subject of scientific
investigation for a century, 1 but defining the responsible mechanisms to guide …

Trauma-induced coagulopathy (TIC) is a clinical scenario spanning the spectrum of
hypocoagulability to hypercoagulability causing a wide range of complications including …

Background Laboratory-based evidence of coagulopathy (LC) is observed in 25-35% of
trauma patients, but clinically-evident coagulopathy (CC) is not well described. Methods …

BACKGROUND Acute traumatic coagulopathy (ATC) occurs after severe injury and shock
and is associated with increased bleeding, morbidity, and mortality. The effects of ATC and …

Objective: To identify an appropriate diagnostic tool for the early diagnosis of acute traumatic
coagulopathy and validate this modality through prediction of transfusion requirements in …