The mammalian small ubiquitin-like modifiers (SUMOs) are actively involved in regulating
differentiation of different cell types. However, the functional differences between SUMO …

The small ubiquitin-related modifiers (SUMOs) regulate nearly every aspect of cellular
function, from gene expression in the nucleus to ion transport at the plasma membrane. In …

Protein SUMOylation (SUMO is small ubiquitin-related modifier) is a dynamic process that is
strictly regulated under physiological and pathological conditions. However, little is known …

Sp1 is a ubiquitously expressed transcription factor that binds GC-rich cis elements. Many
posttranslational modifications have been implicated in the regulation of Sp1 activity. We …

Substantial increases in the conjugation of the main human SUMO paralogs, SUMO1,
SUMO2, and SUMO3, are observed upon exposure to different cellular stressors, and such …

The small ubiquitin-related modifier SUMO reversibly modifies many proteins, including
promoter-specific transcription factors. Genetic studies in both humans and mice indicate …

Sumoylation is a reversible post-translational modification that targets a variety of proteins
mainly within the nucleus, but also in the plasma membrane and cytoplasm of the cell. It …

Small ubiquitin-related modifiers (SUMOs) function as post-translational protein
modifications and regulate nearly every aspect of cellular function. While a single ubiquitin …

Spermatogenesis consists of the mitotic division of spermatogonia, meiosis of
spermatocytes, and postmeiotic differentiation of spermatids, processes tightly controlled by …

Small ubiquitin-like modifier (SUMO) regulates diverse cellular processes through its
reversible, covalent attachment to target proteins. Many SUMO substrates are involved in …