[HTML][HTML] A large-scale genome-wide gene-gene interaction study of lung cancer susceptibility in Europeans with a trans-ethnic validation in Asians

R Zhang, S Shen, Y Wei, Y Zhu, Y Li, J Chen… - Journal of Thoracic …, 2022 - Elsevier
Introduction Although genome-wide association studies have been conducted to investigate
genetic variation of lung tumorigenesis, little is known about gene-gene (G× G) interactions …

[HTML][HTML] Cross-cancer pleiotropic analysis reveals novel susceptibility loci for lung cancer

L Wang, M Zhu, Y Wang, J Fan, Q Sun, M Ji… - Frontiers in …, 2020 - frontiersin.org
Genome-wide association studies (GWASs) have identified hundreds of single nucleotide
polymorphisms (SNPs) associated with cancer risk, several of which have shown pleiotropic …

Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population

Y Li, X Xiao, Y Han, O Gorlova, D Qian, N Leighl… - …, 2018 - academic.oup.com
Non-small cell lung cancer is the most common type of lung cancer. Both environmental and
genetic risk factors contribute to lung carcinogenesis. We conducted a genome-wide …

Association analyses identify multiple new lung cancer susceptibility loci and their interactions with smoking in the Chinese population

J Dong, Z Hu, C Wu, H Guo, B Zhou, J Lv, D Lu… - Nature …, 2012 - nature.com
To find additional susceptibility loci for lung cancer, we tested promising associations from
our previous genome-wide association study (GWAS) of lung cancer in the Chinese …

A cross-tissue transcriptome-wide association study identifies novel susceptibility genes for lung cancer in Chinese populations

M Zhu, J Fan, C Zhang, J Xu, R Yin… - Human Molecular …, 2021 - academic.oup.com
Although dozens of susceptibility loci have been identified for lung cancer in genome-wide
association studies (GWASs), the susceptibility genes and underlying mechanisms remain …

Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women

Z Wang, WJ Seow, K Shiraishi… - Human molecular …, 2016 - academic.oup.com
Genome-wide association studies (GWAS) of lung cancer in Asian never-smoking women
have previously identified six susceptibility loci associated with lung cancer risk. To further …

[HTML][HTML] Systematic analyses of genetic variants in chromatin interaction regions identified four novel lung cancer susceptibility loci

P Ji, D Ding, N Qin, C Wang, M Zhu, Y Li, J Dai… - Journal of …, 2020 - ncbi.nlm.nih.gov
Genome-wide association studies (GWAS) have reported 45 single-nucleotide
polymorphisms (SNPs) that may contribute to the susceptibility of lung cancer, with the …

A genome-wide association study reveals susceptibility variants for non-small cell lung cancer in the Korean population

KA Yoon, JH Park, J Han, S Park, GK Lee… - Human molecular …, 2010 - academic.oup.com
Lung cancer is one of the most common cancers and the major cause of cancer death, both
in Korea and worldwide, with non-small cell lung cancer (NSCLC) as the predominant …

Functional studies of lung cancer GWAS beyond association

E Long, H Patel, J Byun, CI Amos… - Human molecular …, 2022 - academic.oup.com
Fourteen years after the first genome-wide association study (GWAS) of lung cancer was
published, approximately 45 genomic loci have now been significantly associated with lung …

A novel pathway-based approach improves lung cancer risk prediction using germline genetic variations

DC Qian, Y Han, J Byun, HR Shin, RJ Hung… - … Biomarkers & Prevention, 2016 - AACR
Background: Although genome-wide association studies (GWAS) have identified many
genetic variants that are strongly associated with lung cancer, these variants have low …