[HTML][HTML] The immune landscape of cancer

V Thorsson, DL Gibbs, SD Brown, D Wolf, DS Bortone… - Immunity, 2019 - cell.com
In the originally published version of this article, the authors neglected to include Younes
Mokrab and Aaron M. Newman as co-authors and misspelled the names of authors Charles …

[HTML][HTML] The immune landscape of cancer

V Thorsson, DL Gibbs, SD Brown, D Wolf, DS Bortone… - Immunity, 2018 - cell.com
We performed an extensive immunogenomic analysis of more than 10,000 tumors
comprising 33 diverse cancer types by utilizing data compiled by TCGA. Across cancer …

A novel scoring method based on RNA‐Seq immunograms describing individual cancer‐immunity interactions

Y Kobayashi, Y Kushihara, N Saito… - Cancer …, 2020 - Wiley Online Library
Because of the complexity of cancer‐immune system interactions, combinations of
biomarkers will be required for predicting individual patient responses to treatment and for …

[HTML][HTML] Conservation of immune gene signatures in solid tumors and prognostic implications

J Chifman, A Pullikuth, JW Chou, D Bedognetti… - BMC cancer, 2016 - Springer
Background Tumor-infiltrating leukocytes can either limit cancer growth or facilitate its
spread. Diagnostic strategies that comprehensively assess the functional complexity of …

TIMER2. 0 for analysis of tumor-infiltrating immune cells

T Li, J Fu, Z Zeng, D Cohen, J Li, Q Chen… - Nucleic acids …, 2020 - academic.oup.com
Tumor progression and the efficacy of immunotherapy are strongly influenced by the
composition and abundance of immune cells in the tumor microenvironment. Due to the …

[HTML][HTML] The immune score as a new possible approach for the classification of cancer

J Galon, F Pagès, FM Marincola, M Thurin… - Journal of translational …, 2012 - Springer
The outcome prediction in cancer is usually achieved by evaluating tissue samples obtained
during surgical removal of the primary tumor focusing on their histopathological …

Immune cell gene signatures for profiling the microenvironment of solid tumors

AJ Nirmal, T Regan, BB Shih, DA Hume, AH Sims… - Cancer immunology …, 2018 - AACR
The immune composition of the tumor microenvironment regulates processes including
angiogenesis, metastasis, and the response to drugs or immunotherapy. To facilitate the …

[HTML][HTML] A mutation-based gene set predicts survival benefit after immunotherapy across multiple cancers and reveals the immune response landscape

J Long, D Wang, A Wang, P Chen, Y Lin, J Bian… - Genome medicine, 2022 - Springer
Background Immune checkpoint inhibitor (ICI) therapy has revolutionized the treatment of
many cancers. However, the limited population that benefits from ICI therapy makes it …

Immune contexture, immunoscore, and malignant cell molecular subgroups for prognostic and theranostic classifications of cancers

E Becht, NA Giraldo, C Germain, A de Reyniès… - Advances in …, 2016 - Elsevier
The outcome of tumors results from genetic and epigenetic modifications of the transformed
cells and also from the interactions of the malignant cells with their tumor microenvironment …

[HTML][HTML] Immune cell profiling in cancer: molecular approaches to cell-specific identification

YA Lyons, SY Wu, WW Overwijk, KA Baggerly… - NPJ precision …, 2017 - nature.com
The immune system has many important regulatory roles in cancer development and
progression. Given the emergence of effective immune therapies against many cancers …