Objectives: A relationship between reduced brain tissue oxygenation and poor outcome
following severe traumatic brain injury has been reported in observational studies. We …

Cerebral ischemia is a well-recognized contributor to high morbidity and mortality after
traumatic brain injury (TBI). Standard of care treatment aims to maintain a sufficient oxygen …

Object Cerebral ischemia is the leading cause of preventable death in cases of major
trauma with severe traumatic brain injury (TBI). Intracranial pressure (ICP) control and …

Object The authors sought to describe changes in clinical management associated with
brain tissue oxygen (PbO 2) monitoring and how these changes affected outcomes and …

Object The object of this study was to determine whether brain tissue oxygen (PbtO 2)–
based therapy or intracranial pressure (ICP)/cerebral perfusion pressure (CPP)–based …

Background Optimisation of brain oxygenation might improve neurological outcome after
traumatic brain injury. The OXY-TC trial explored the superiority of a strategy combining …

Introduction Management of traumatic brain injury (TBI) includes invasive monitoring to
prevent secondary brain injuries. Intracranial pressure (ICP) monitor is the main …

Object Control of intracranial pressure (ICP) and cerebral perfusion pressure (CPP) is the
foundation of traumatic brain injury (TBI) management. In this study, the authors examined …

Object. An intracranial pressure (ICP) monitor, from which cerebral perfusion pressure (CPP)
is estimated, is recommended in the care of severe traumatic brain injury (TBI) …

Objective: To evaluate the concept of a cerebrovascular pressure reactivity-guided optimal
cerebral perfusion pressure after traumatic brain injury by analyzing the relationship …