Compounds that can protect cells from the effects of radiation are important for clinical use,
in the event of an accidental or terrorist-generated radiation event, and for astronauts …

Repair of DNA damage through homologous recombination (HR) pathways plays a crucial
role in maintaining genome stability. However, overstimulation of HR pathways in response …

Amifostine protects normal cells from DNA damage induction by ionizing radiation or
chemotherapeutics, whereas cancer cells typically remain uninfluenced. While confirming …

Abstract Murley, JS, Nantajit, D., Baker, KL, Kataoka, Y., Li, JJ and Grdina, DJ Maintenance
of Manganese Superoxide Dismutase (SOD2)-Mediated Delayed Radioprotection Induced …

WR-1065, the free-thiol form of WR-2721, has radioprotective effects in various biological
systems. We measured the efficiency of WR-1065 in modifying the induction of chromosome …

The effects of cycloheximide (CHX) and 2-[(aminopropyl)-amino] ethanethiol (WR-1065),
each alone or in combination, on radiation-induced mutation induction at the hypoxanthine …

Background: The aminothiol WR1065 is a highly effective free radical scavenger which can
protect cells from the cytotoxic effects of ionizing radiation. Currently, WR1065 is used …

The effects of the radioprotector 2-[(aminopropyl) amino] ethanethiol (WR-1065) on radiation-
induced cell killing and mutagenesis at the hypoxanthine-guanine phosphoribosyl …

Exposure to the thiolamine radioprotector N (2-mercaptoethyl)-1, 3-propanediamine (WR-
1065) induced apoptosis in the mouse TB8. 3 hybridoma after a 60-min (LD50= 4.5 mm) or …

Abstract N-(2-mercaptoethyl)-lt3-diaminopropane (WR1065) protects against radiation-
induced cell killing and mutagenesis at the hypoxanthine-guanine phosphoribosyl …