IgG antibodies are important mediators of vaccine-induced immunity through complement-
and Fc receptor-dependent effector functions. Both are influenced by the composition of the …

Although vaccination efforts have expanded, there are still gaps in our understanding
surrounding the immune response to SARS-CoV-2. Measuring IgG Fc glycosylation …

Messenger RNA-based vaccines against COVID-19 induce a robust anti-SARS-CoV-2
antibody response with potent viral neutralization activity. Antibody effector functions are …

Background The new types of mRNA-containing lipid nanoparticle vaccines BNT162b2 and
mRNA-1273 and the adenovirus-based vaccine AZD1222 were developed against SARS …

INTRODUCTION Antibody function is often considered static and mostly determined by
isotype and subclass. The conserved N-linked glycan at position 297 in the Fc domain of …

IgG antibodies are crucial for protection against invading pathogens. A highly conserved N-
linked glycan within the IgG-Fc-tail, essential for IgG function, shows variable composition in …

Summary Background Afucosylated IgG1 responses have only been found against
membrane-embedded epitopes, including anti-S in SARS-CoV-2 infections. These …

The nature of the immune responses associated with COVID‐19 pathogenesis and disease
severity, as well as the breadth of vaccine coverage and duration of immunity, is still unclear …

The glycosylation of viral envelope proteins can play important roles in virus biology and
immune evasion. The spike (S) glycoprotein of severe acute respiratory syndrome …

The world-wide COVID-19 pandemic has promoted a series of alternative vaccination
strategies aiming to elicit neutralizing adaptive immunity in the human host. However …