The effects of mechanical loading on the osteoblast phenotype remain unclear because of
many variables inherent to the current experimental models. This study reports on utilization …

Mechanical loading is an essential environmental factor in skeletal homeostasis, but the
response of osteoblast-associated genes to mechanical osteogenic signal is largely …

Mechanical loading is an important regulatory factor in alveolar bone homeostasis, and
plays an essential role in maintaining the structure and mass of the alveolar processes …

A better understanding of cellular and molecular mechanisms involved in response to
mechanical stress is a prerequisite for future improvements in orthodontic treatment. To …

Reverse transcript polymerase chain reaction (RT-PCR) was developed for use in situ to
measure mechanically mediated changes in gene expression activity in osteocytes within …

Osteocytes have been proposed to be the cells primarily responsible for sensing the effects
of mechanical loading in bone. Osteocytes respond to loading in vivo, and have been shown …

Olson C., Uribe F., Kalajzic Z., Utreja A., Nanda R., Rowe D., Wadhwa S. Orthodontic tooth
movement causes decreased promoter expression of collagen type 1, bone sialoprotein and …

Previous studies have reported changes in proliferation, second-messenger generation and
activation of various cellular processes when osteoblasts have been mechanically …

Orthodontic tooth movement results from the combinational process of both bone resorption
and formation in the compressive and tension sides, respectively. However, the genes …

The forces that orthodontic appliances apply to the teeth are transmitted through the
periodontal ligament (PDL) to the supporting alveolar bone, leading to the deposition or …