Role of nitric oxide and prostaglandins in gastroprotection induced by capsaicin and papaverine

T Brzozowski, D Drozdowicz, A Szlachcic… - Digestion, 1993 - karger.com
Capsaicin and papaverine are potent vasorelaxants with strong gastroprotective activity
against damage induced by absolute ethanol. This protection was originally attributed to the …

Studies on gastroprotection induced by capsaicin and papaverine

T Brzozowski, D Drozdowicz, J Majka… - Journal of Physiology …, 1992 - agro.icm.edu.pl
Capsaicin and papaverine are potent vasorelaxants with strong gastroprotective activity
against damage induced by absolute ethanol. This protection was originally attributed to the …

Nitric oxide in gastroprotection by sucralfate, mild irritant, and nocloprost: role of mucosal blood flow

SJ Konturek, T Brzozowski, J Majka, A Szlachcic… - Digestive diseases and …, 1994 - Springer
Pretreatment with sucralfate is known to protect gastric mucosa against the damaging effect
of strong irritants, and this protection is accompanied by an increase in mucosal blood flow …

Gastroprotective and ulcer healing effects of nitric oxide-releasing non-steroidal anti-inflammatory drugs

T Brzozowski, PC Konturek, SJ Konturek… - Digestive and Liver …, 2000 - Elsevier
Background & Aim. New class of nitric oxide-releasing non-steroidal anti-inflammatory drugs
was shown to inhibit cyclooxygenase and prostaglandin generation without causing …

Implications of nitric oxide in the action of cytoprotective drugs on gastric mucosa

SJ Konturek, T Brzozowski, J Majka… - Journal of clinical …, 1993 - journals.lww.com
Cytoprotective drugs, including sucralfate, colloidal bismuth (De-Nol), aluminium-containing
antacids (Maalox), carbenoxolone-like agents (sofalcone), and stable PGE 2 analogues …

Paradoxical effects of L-arginine on gastric mucosal integrity

JGP Ferraz, A Tigley, JL Wallace - European journal of pharmacology, 1994 - Elsevier
Nitric oxide can exert either protective or damaging effects on the gastric mucosa. To further
explore the role of nitric oxide in the modulation of gastric mucosal defense, the effects of …

Roles of prostaglandins, nitric oxide and the capsaicin-sensitive sensory nerves in gastroprotection produced by ecabet sodium.

M Kinoshita, E Kume, H Tamaki - Journal of pharmacology and experimental …, 1995 - ASPET
We determined the mechanism of the gastroprotective effects of ecabet sodium (ecabet), a
new antiulcer drug. Ecabet (12.5-100 mg/kg po) dose-dependently protected gastric mucosa …

Ketotifen and nitroxides decrease capsaicin-augmented ethanol-induced gastric damage in rats

F Karmeli, R Eliakim, E Okon… - Digestive diseases and …, 1995 - Springer
Systemic administration of capsaicin aggravates ethanol-induced injury of rat gastric
mucosa. We evaluated the effect of subcutaneous administration of capsaicin on the gastric …

Mechanism of prevention by capsaicin of ethanol‐induced gastric mucosal injury–a study in the rat using intravital microscopy

T Saeki, T Ohno, K Boku, K Saigenji… - Alimentary …, 2000 - Wiley Online Library
Background: Capsaicin acts specifically on primary afferent neurones to release
neuropeptides, including calcitonin gene‐related peptide (CGRP), and prevents ethanol …

The role of nitric oxide and sulphydryls in gastric mucosal protection induced by sodium cromoglycate in rats

ATM Mobarok Ali - Journal of pharmacy and pharmacology, 1995 - academic.oup.com
The role of endogenous nitric oxide and sulphydryls in gastric protection afforded by sodium
cromoglycate against ethanol-induced gastric lesions was studied in rats. Drugs were …