Prior extended daily access to cocaine elevates the reward threshold in a conditioned place preference test
ZI Su, J Wenzel, A Ettenberg… - Addiction biology, 2014 - Wiley Online Library
We have previously shown that extended‐access subjects exhibit heightened motivation for
cocaine in the runway model, as reflected by reduced number of retreats. This heightened …
cocaine in the runway model, as reflected by reduced number of retreats. This heightened …
Effects of extended cocaine conditioning in the reinstatement of place preference
M Rodríguez-Arias, A Castillo, M Daza-Losada… - Physiology & …, 2009 - Elsevier
Rats allowed extended access to cocaine self-administration develop a number of
symptoms of addiction, such as greater susceptibility to drug-induced relapse. Using the …
symptoms of addiction, such as greater susceptibility to drug-induced relapse. Using the …
On the persistence of cocaine-induced place preferences and aversions in rats
ZI Su, A Santoostaroam, J Wenzel, A Ettenberg - Psychopharmacology, 2013 - Springer
Rationale Rats develop preferences for places associated with the immediate rewarding
effects of cocaine and aversions for places paired with the drug's delayed negative effects …
effects of cocaine and aversions for places paired with the drug's delayed negative effects …
Pre-treatment with high doses of cocaine decreases the reinforcing effects of cocaine in the conditioned place preference paradigm
C Manzanedo, MP Garcia-Pardo, M Rodríguez-Arias… - Neuroscience …, 2012 - Elsevier
The aim of the present study was to determine if pre-exposure to high doses of cocaine can
subsequently alter the rewarding effects of this drug. Adult male mice received a …
subsequently alter the rewarding effects of this drug. Adult male mice received a …
Cocaine, but not alcohol, reinstates cocaine-induced place preferences
GD Busse, AL Riley - Pharmacology Biochemistry and Behavior, 2004 - Elsevier
Alcohol has been reported to modulate the reinforcing and aversive properties of cocaine.
Given these effects, the present study examined whether this interaction could be extended …
Given these effects, the present study examined whether this interaction could be extended …
Conditioned place preference after single doses or “binge” cocaine in C57BL/6J and 129/J mice
Y Zhang, JR Mantsch, SD Schlussman, A Ho… - Pharmacology …, 2002 - Elsevier
The rewarding effect of cocaine as reflected by the development of conditioned place
preference was examined in C57BL/6J and 129/J mice. Cocaine was administered in a …
preference was examined in C57BL/6J and 129/J mice. Cocaine was administered in a …
Cocaine-induced conditioned place preference: reinstatement by priming injections of cocaine after extinction
To explore the way in which drugs act to reinstate drug-seeking behavior, we studied drug-
induced reinstatement of a cocaine-induced conditioned place preference (CPP). In a series …
induced reinstatement of a cocaine-induced conditioned place preference (CPP). In a series …
Locomotor response to novelty does not predict cocaine place preference conditioning in rats
W Gong, DB Neill, JB Justice Jr - Pharmacology Biochemistry and Behavior, 1996 - Elsevier
Previous studies have demonstrated that rats showing a strong locomotor response to a
novel environment have a greater locomotor response to psychostimulant drugs and more …
novel environment have a greater locomotor response to psychostimulant drugs and more …
The failure of some rats to acquire intravenous cocaine self-administration is attributable to conditioned place aversion
DJ Rademacher, KA Anders, KJ Thompson… - Behavioural brain …, 2000 - Elsevier
Although cocaine administration in humans includes euphoric and anxiogenic effects, the
latter are less well understood. Acute cocaine administration produces aversive effects …
latter are less well understood. Acute cocaine administration produces aversive effects …
Sensitization to the conditioned rewarding effects of cocaine: pharmacological and temporal characteristics.
TS Shippenberg, CH Heidbreder - Journal of Pharmacology and …, 1995 - ASPET
An unbiased place preference conditioning procedure was used to determine whether the
repeated administration of cocaine results in sensitization to its conditioned rewarding …
repeated administration of cocaine results in sensitization to its conditioned rewarding …