Racial differences in genome-wide methylation profiling and gene expression in breast tissues from healthy women

MA Song, TM Brasky, C Marian, DY Weng, C Taslim… - Epigenetics, 2015 - Taylor & Francis
Breast cancer is more common in European Americans (EAs) than in African Americans
(AAs) but mortality from breast cancer is higher among AAs. While there are racial …

Racial variation in breast tumor promoter methylation in the Carolina Breast Cancer Study

K Conway, SN Edmiston, CK Tse, C Bryant… - … Biomarkers & Prevention, 2015 - AACR
Abstract Background: African American (AA) women are diagnosed with more advanced
breast cancers and have worse survival than white women, but a comprehensive …

[HTML][HTML] Genome-wide methylation patterns provide insight into differences in breast tumor biology between American women of African and European ancestry

CB Ambrosone, AC Young, LE Sucheston, D Wang… - Oncotarget, 2014 - ncbi.nlm.nih.gov
American women of African ancestry (AA) are more likely than European-Americans (EA) to
be diagnosed with aggressive, estrogen receptor (ER) negative breast tumors; mechanisms …

Epigenome-wide methylation in DNA from peripheral blood as a marker of risk for breast cancer

G Severi, MC Southey, DR English, C Jung… - Breast cancer research …, 2014 - Springer
Aberrant DNA methylation is a key feature of breast carcinoma. We aimed to test the
association between breast cancer risk and epigenome-wide methylation in DNA from …

DNA methylation and breast cancer risk: an epigenome-wide study of normal breast tissue and blood

K Ennour-Idrissi, D Dragic, E Issa, A Michaud… - Cancers, 2020 - mdpi.com
Simple Summary As known breast cancer risk factors do not accurately predict the risk of
developing breast cancer, breast cancer screening is still based solely on age. At the …

Age-related DNA methylation in normal breast tissue and its relationship with invasive breast tumor methylation

KC Johnson, DC Koestler, C Cheng, BC Christensen - Epigenetics, 2014 - Taylor & Francis
Age is a key risk factor for breast cancer and epigenetic alterations may contribute to age-
related increases in breast cancer risk, though the relation of age-related methylation in …

DNA methylation and hormone receptor status in breast cancer

EV Benevolenskaya, AB Islam, H Ahsan, MG Kibriya… - Clinical …, 2016 - Springer
Background We examined whether differences in tumor DNA methylation were associated
with more aggressive hormone receptor-negative breast cancer in an ethnically diverse …

Genome‐wide methylation screen in low‐grade breast cancer identifies novel epigenetically altered genes as potential biomarkers for tumor diagnosis

M Faryna, C Konermann, S Aulmann… - The FASEB …, 2012 - Wiley Online Library
Aberrant DNA methylation constitutes a well‐established epigenetic marker for breast
cancer. Changes in methylation early in cancer development may be clinically relevant for …

Epigenome-wide DNA methylation and risk of breast cancer: a systematic review

K Ennour-Idrissi, D Dragic, F Durocher, C Diorio - BMC cancer, 2020 - Springer
Background DNA methylation is a potential biomarker for early detection of breast cancer.
However, robust evidence of a prospective relationship between DNA methylation patterns …

Genetically predicted levels of DNA methylation biomarkers and breast cancer risk: data from 228 951 women of European descent

Y Yang, L Wu, XO Shu, Q Cai, X Shu… - JNCI: Journal of the …, 2020 - academic.oup.com
Background DNA methylation plays a critical role in breast cancer development. Previous
studies have identified DNA methylation marks in white blood cells as promising biomarkers …