Analyzing the changes in the brain material properties after a mild traumatic brain injury—A pilot study

E Kwon, S Holdsworth, SJ Guild, M Scadeng… - Engineering …, 2021 - Wiley Online Library
Traumatic brain injury (TBI) is a major health challenge, is very difficult to diagnose, and
currently has no accepted treatment options. The difficulty in diagnosis is due to the complex …

[HTML][HTML] Material properties of human brain tissue suitable for modelling traumatic brain injury

DB MacManus, M Ghajari - Brain Multiphysics, 2022 - Elsevier
Finite element (FE) brain models have revolutionised research on the biomechanics of
traumatic brain injury (TBI). The accuracy and reliability of results arising from brain models …

Investigation of cross-species scaling methods for traumatic brain injury using finite element analysis

T Wu, J Antona-Makoshi, A Alshareef… - Journal of …, 2020 - liebertpub.com
Scaling methods are used to relate animal exposure data to humans by determining
equivalent biomechanical impact conditions that result in similar tissue-level mechanics for …

Material properties of the brain in injury-relevant conditions–Experiments and computational modeling

W Zhao, B Choate, S Ji - Journal of the mechanical behavior of biomedical …, 2018 - Elsevier
Material properties of the brain have been extensively studied but remain poorly
characterized. The vast variations in constitutive models and material constants are well …

[HTML][HTML] State-of-the-art modeling and simulation of the brain's response to mechanical loads

MF Horstemeyer, MB Panzer, RK Prabhu - Annals of biomedical …, 2019 - Springer
Traumatic Brain Injuries (TBI) are one of the most common yet least understood injuries to
the human body. In the United States in 2013, an estimated 2.8 million hospital emergency …

[图书][B] Computational analysis of in vivo brain trauma

H Mao - 2009 - search.proquest.com
Traumatic brain injury (TBI) continues to be a serious societal problem affecting at least 1.4
million Americans each year. Despite the significance of this public health problem and long …

Effect of inter-species, gender, and breeding on the mechanical behavior of brain tissue

F Pervin, WW Chen - NeuroImage, 2011 - Elsevier
Mechanical response of brain tissue deforming at high rates are needed to build high-fidelity
computer models for traumatic brain injury (TBI) studies. Different types of mammalian brains …

[PDF][PDF] Identifying Traumatic Brain Injury (TBI) Thresholds Using Animal and Human Finite Element Models Based on In-Vivo Impact Test Data

K Yates, C Untaroiu - Proc. 14th Int. LS-DYNA Users Conf …, 2016 - lsdyna.ansys.com
Traumatic brain injuries (TBIs) cause roughly 50,000 deaths per year in America. In order to
lessen the severity or prevent TBIs, accurate dummy models, simulations, and injury risk …

A mechanics theory for the exploration of a high-throughput, sterile 3D in vitro traumatic brain injury model

Y Wan, RD González-Cruz, D Hoffman-Kim, H Kesari - 2023 - researchsquare.com
Brain injuries resulting from mechanical trauma represent an ongoing global public health
issue. Several in vitro and in vivo models for traumatic brain injury (TBI) continue to be …

[HTML][HTML] A machine learning approach to investigate the uncertainty of tissue-level injury metrics for cerebral contusion

A Menichetti, L Bartsoen, B Depreitere… - … in bioengineering and …, 2021 - frontiersin.org
Controlled cortical impact (CCI) on porcine brain is often utilized to investigate the
pathophysiology and functional outcome of focal traumatic brain injury (TBI), such as …