Evaluation of colchicine with or without praziquantel therapy in the control of hepatic fibrosis in murine schistosomiasis

AA Badawy, NM El-Badrawy, SS Mansy, MM Akl… - Pharmacological …, 1996 - Elsevier
Colchicine alone or following praziquantel was given to mice infected withSchistosoma
mansonieither 6 or 10 weeks post infection. Praziquantel increased body weight gain …

Colchicine therapy for hepatic murine schistosomal fibrosis: image analysis and serological study

AA BADAWY, NM EL‐BADRAWY… - International journal …, 1999 - Wiley Online Library
Colchicine in a dose of 200 μg kg body weight/day (5 days/week) was administered to
groups of Schistosoma mansoni infected mice 12 weeks post infection, either alone or …

Effect of praziquantel on hepatic fibrosis in experimental schistosomiasis mansoni

NM El-Badrawy, HI Hassanein, SS Botros… - … and molecular pathology, 1988 - Elsevier
The effect of specific chemotherapy on hepatic fibrosis was studied in Swiss albino mice
infected with Schistosoma mansoni. The effect of treatment with praziquantel at 8, 12, and 20 …

Colchicine reduces hepatic fibrosis in mice infected with Schistosoma japonicum

J Jiang, C Zhong, Y Yu, Q Zhang - Chinese Medical Journal, 1996 - mednexus.org
OBJECTIVE Colchicine has been used clinically to treat hepatic cirrhosis caused by multiple
etiologies. MATERIALS AND METHODS The effect of colchicine on the liver fibrosis of mice …

Effect of praziquantel on hepatic murine schistosomiasis: histopathological study, immunolocalization of type III procollagen and serological analysis.

AA Badawy, NM El-Badrawy, GM Nada, AA El-Garem… - 1991 - cabidigitallibrary.org
Histopathological changes in the liver, immunofluorescent detection of type III procollagen,
and liver function parameters were studied in Swiss albino mice infected with Schistosoma …

Ultrastructural studies on effects of colchicine in treating hepatic fibrosis of schistosomiasis rabbits

JW Jiang, CS Zhong, YF Yu… - Zhongguo ji sheng …, 1990 - pubmed.ncbi.nlm.nih.gov
8 rabbits were infected percutaneously with the cercariae of Schistosoma japonicum. After
hepatic fibrosis had developed in these rabbits 4 months after infection, 4 out of the 8 …

Histopathological evidences for the antifibrogenic effect of colchicine in schistosomiasis mansoni in mice.

MF Montasser, TA Younis, IA Fahmy… - Journal of the …, 1994 - europepmc.org
Colchicine treated mice showed significant decrease in prevalence of fibrocellular and
fibrocellular and fibrous granulomas in liver specimens compared to corresponding control …

Serologic and ultrasonographic parameters of praziquantel treatment of hepatic fibrosis in Schistosoma japonicum infection.

H Ohmae, M Tanaka, T Nara, H Utsunomiya… - The American journal …, 1991 - europepmc.org
We describe the parameters useful in evaluating the development of hepatic fibrosis in
Schistosoma japonicum infection, as well as its improvement after treatment with …

Effect of praziquantel on the distribution of interstitial collagen types I and III and basement membrane collagen types IV and V in murine hepatic schistosomiasis

NM El-Badrawy, AMA Hadi, B Voss, AA Metwally… - Transactions of the …, 1991 - Elsevier
The effect of specific chemotherapy (praziquantel) on liver function tests and on the
distribution of collagen types I, III, IV and V was studied by indirect immunofluorescence in …

Reversal of hepatic fibrosis after praziquantel therapy of murine schistosomiasis.

SH Morcos, MT Khayyal, MM Mansour… - The American journal …, 1985 - europepmc.org
We examined the effect of parasitologic cure of S. mansoni infection on liver fibrosis in mice.
Praziquantel, 250 mg/kg body weight, was administered orally to mice 8 weeks after …