Epithelial ovarian cancer (EOC) is hallmarked by a high degree of heterogeneity. To
address this heterogeneity, a classification scheme was developed based on gene …

Ovarian cancer has a poor prognosis, with different outcomes for different patients. The
mechanism underlying this poor prognosis and heterogeneity is not well understood. We …

Epithelial ovarian cancer represents the most lethal gynecological malignancy in the
developed world, and can be divided into five main histological subtypes: high grade …

Background Epithelial ovarian cancer (EOC) remains one of the leading causes of cancer-
related deaths among women worldwide, despite gains in diagnostics and treatments made …

The hallmarks of ovarian cancer encompass the development of resistance, disease
recurrence and poor prognosis. Ovarian cancer cells express gene signatures which pose …

Over the past 40 years, the treatment of ovarian cancer has undoubtedly improved as a
result of better multi-modality care and platinum-based chemotherapy. More recently, the …

Purpose: Recent progress in understanding the molecular biology of epithelial ovarian
cancer has not yet translated into individualized treatment for these women or improvements …

Ovarian carcinoma (OC) is an umbrella term for multiple distinct diseases (histotypes), each
with their own developmental origins, clinical behaviour and molecular profile. Accordingly …

Ovarian carcinoma (OC) is the most lethal gynecological malignancy. Response to platinum-
based chemotherapy is poor in some patients and, thus, current research is focusing on new …

Ovarian cancer encompasses a collection of neoplasms with distinct clinicopathological and
molecular features and prognosis. Despite there being a variety of ovarian cancer subtypes …