CRASH-2 (Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage) intracranial bleeding study: the effect of tranexamic acid in traumatic brain injury …
P Perel, R Al-Shahi Salman… - Health technology …, 2012 - researchonline.lshtm.ac.uk
BACKGROUND: Tranexamic acid (TXA) has been shown to reduce blood loss in surgical
patients and the risk of death in patients with traumatic bleeding, with no apparent increase …
patients and the risk of death in patients with traumatic bleeding, with no apparent increase …
Tranexamic acid for traumatic brain injury: a systematic review and meta-analysis
S Zehtabchi, SGA Baki, L Falzon… - The American journal of …, 2014 - Elsevier
Objective The antifibrinolytic agent tranexamic acid (TXA) has demonstrated clinical benefit
in trauma patients with severe bleeding, but its effectiveness in patients with traumatic brain …
in trauma patients with severe bleeding, but its effectiveness in patients with traumatic brain …
Tranexamic acid for patients with traumatic brain injury: a randomized, double-blinded, placebo-controlled trial
S Yutthakasemsunt, W Kittiwatanagul… - BMC emergency …, 2013 - Springer
Background Traumatic brain injury (TBI) is commonly accompanied by intracranial bleeding
which can worsen after hospital admission. Tranexamic acid (TXA) has been shown to …
which can worsen after hospital admission. Tranexamic acid (TXA) has been shown to …
[HTML][HTML] Tranexamic acid for significant traumatic brain injury (the CRASH-3 trial): statistical analysis plan for an international, randomised, double-blind, placebo …
Background: Worldwide, traumatic brain injury (TBI) kills or hospitalises over 10 million
people each year. Early intracranial bleeding is common after TBI, increasing the risk of …
people each year. Early intracranial bleeding is common after TBI, increasing the risk of …
[HTML][HTML] Use of tranexamic acid in major trauma: a sex-disaggregated analysis of the Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage (CRASH …
Background Women are less likely than men to receive some emergency treatments. This
study examines whether the effect of tranexamic acid (TXA) on mortality in trauma patients …
study examines whether the effect of tranexamic acid (TXA) on mortality in trauma patients …
Tranexamic acid in trauma: how should we use it?
I Roberts - Journal of Thrombosis and Haemostasis, 2015 - Wiley Online Library
Tranexamic acid (TXA) reduces blood loss by inhibiting the enzymatic breakdown of fibrin. It
is often used in surgery to decrease bleeding and the need for blood transfusion. In 2011 …
is often used in surgery to decrease bleeding and the need for blood transfusion. In 2011 …
Effect of tranexamic acid in traumatic brain injury: a nested randomised, placebo controlled trial (CRASH-2 Intracranial Bleeding Study)
Crash-2 Collaborators - Bmj, 2011 - bmj.com
Objective To assess the effect of tranexamic acid (which reduces bleeding in surgical
patients and reduces mortality due to bleeding in trauma patients) on intracranial …
patients and reduces mortality due to bleeding in trauma patients) on intracranial …
[HTML][HTML] Tranexamic acid to reduce head injury death in people with traumatic brain injury: the CRASH-3 international RCT.
I Roberts, H Shakur-Still, A Aeron-Thomas… - Health Technology …, 2021 - ncbi.nlm.nih.gov
BACKGROUND Tranexamic acid safely reduces mortality in traumatic extracranial bleeding.
Intracranial bleeding is common after traumatic brain injury and can cause brain herniation …
Intracranial bleeding is common after traumatic brain injury and can cause brain herniation …
[HTML][HTML] Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a …
T CRASH - The Lancet, 2019 - Elsevier
Background Tranexamic acid reduces surgical bleeding and decreases mortality in patients
with traumatic extracranial bleeding. Intracranial bleeding is common after traumatic brain …
with traumatic extracranial bleeding. Intracranial bleeding is common after traumatic brain …
Implementation of tranexamic acid for bleeding trauma patients: a longitudinal and cross-sectional study
Objective To describe the use of tranexamic acid (TXA) in trauma care in England and
Wales since the Clinical Randomization of an Antifibrinolytic in Significant Hemorrhage …
Wales since the Clinical Randomization of an Antifibrinolytic in Significant Hemorrhage …
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