The free radical theory of ageing posits that accrual of oxidative damage underlies the
increased cellular, tissue and organ dysfunction and failure associated with advanced age …

Currently, the oxidative stress (or free radical) theory of aging is the most popular
explanation of how aging occurs at the molecular level. While data from studies in …

The free radical theory of ageing provided an intellectual framework for many laboratories
working on ageing. However, experimental and clinical evidence showing that high doses of …

Most organisms experience progressive declines in physiological function as they age.
Since this senescence of function is thought to underlie the decrease in quality of life in …

Oxidative stress is reputed to be a significant contributor to the aging process and a key
factor affecting species longevity. The tremendous natural variation in maximum species …

Most evidence indicates that aging is a result of normal metabolic processes that are
essential for life. Thus an important approach in biogerontology is to identify specific …

The widely accepted oxidative stress theory of aging postulates that aging results from
accumulation of oxidative damage. Surprisingly, data from the longest-living rodent known …

Previous studies have shown that longevity is associated with enhanced cellular stress
resistance. This observation supports the disposable soma theory of aging, which suggests …

A series of studies over many years has conclusively disproved the hypothesis that longevity
in warm-blooded animals (homeotherms) correlates with high levels of antioxidant enzymes …

The Free Radical/Oxidative Stress Theory of Aging, which was first proposed in 1956, is
currently one of the most popular explanations for how aging occurs at the …