Objective To assess reliability and discriminative validity of cartilage compositional magnetic
resonance imaging (MRI) in knee osteoarthritis (OA). Design The study was carried out per …

Objective Early and non-invasive detection of osteoarthritis (OA) is required to enable early
treatment and monitoring of interventions. Some of the earliest signs of OA are the change in …

OBJECTIVE: To summarize literature on the responsiveness and reliability of MRI-based
measures of knee osteoarthritis (OA) structural change. METHODS: A literature search was …

MRI-based cartilage compositional analysis shows biochemical and microstructural
changes at early stages of osteoarthritis before changes become visible with structural MRI …

Osteoarthritis (OA), a leading cause of disability, affects 27 million people in the United
States and its prevalence is rising along with the rise in obesity. So far, biomechanical or …

Objective Quantitative magnetic resonance imaging (MRI) of articular cartilage represents a
powerful tool in osteoarthritis (OA) research, but has so far been confined to a field strength …

Purpose To prospectively determine the reproducibility of quantitative magnetic resonance
(MR) imaging biomarkers of the morphology and composition (spin lattice relaxation time in …

Background In patients with osteoarthritis, a detailed assessment of degenerative cartilage
disease is important to recommend adequate treatment. Using a representative sample of …

Objective T scores (an indicator of the difference between patients and young healthy
subjects) and Z scores (an indicator of the difference between patients and age‐matched …

OBJECTIVE: Magnetic resonance imaging (MRI) of articular cartilage has evolved to be an
important tool in research on cartilage (patho) physiology and osteoarthritis (OA). MRI …