Some successful chemotherapeutics, notably anthracyclines and oxaliplatin, induce a type
of cell stress and death that is immunogenic, hence converting the patient's dying cancer …

Retrospective clinical data indicate that cardiac glycosides (CGs), notably digoxin, prolong
the survival of carcinoma patients treated with conventional chemotherapy. CGs are known …

Cardiac glycosides (CGs) are natural compounds sharing the ability to operate as potent
inhibitors of the plasma membrane Na+/K+-ATPase, hence promoting—via an indirect …

The class of steroid-like compounds designated cardiac glycosides includes well-known
drugs such as digoxin, digitoxin, and ouabain. Their continued efficacy in treatment of …

Cardiac glycosides (CGs) have a long history of treating cardiac diseases. However, recent
reports have suggested that CGs also possess anticancer and antiviral activities. The …

Cardiac glycosides (CGs) are natural compounds widely used in the treatment of several
cardiac conditions and more recently have been recognized as potential antitumor …

Cardiac glycosides, also known as cardiotonic steroids, are a group of natural products that
share a steroid‐like structure with an unsaturated lactone ring and the ability to induce …

Cardiac glycosides (CGs) are approved for the treatment of cardiovascular alterations and
their known cellular target is the alpha subunit of the sodium (Na+)/potassium (K+)-ATPase …

Background Cardiac glycosides are Na+/K+-pump inhibitors widely used to treat heart
failure. They are also highly cytotoxic, and studies have suggested specific anti-tumor …

Cardiac glycosides have been reported to exhibit cytotoxic activity against several different
cancer types, but studies against colorectal cancer are lacking. In a screening procedure …