Eukaryotic positive-strand RNA viruses replicate using the membrane-bound replicase
complexes, which contain multiple viral and host components. Virus infection induces the …

Positive-strand RNA [(+) RNA] viruses are responsible for numerous human, animal, and
plant diseases. Because of the limiting coding capacity of (+) RNA viruses, their replication …

The replication of the genome of positive-strand RNA viruses depends on their own RNA
replicase complexes. Substantial advances in the experimental approaches used to …

Positive-strand RNA viruses replicate their genomes on membranes with virus-induced
rearrangements such as single-or double-membrane vesicles, but the mechanisms of such …

Many RNA viruses remodel intracellular membranes to generate specialized sites for RNA
replication. How membranes are remodeled and what properties make them conducive for …

Recognition of RNA templates by viral replicase proteins is one of the key steps in the
replication process of all RNA viruses. However, the mechanisms underlying this …

Infection of cells with poliovirus induces a massive intracellular membrane reorganization to
form vesicle-like structures where viral RNA replication occurs. The mechanism of …

As sessile organisms, plants have to accommodate to rapid changes in their surrounding
environment. Reactive oxygen species (ROS) act as signaling molecules to transduce biotic …

Positive-strand RNA viruses require host intracellular membranes for replicating their
genomic RNAs. In this study, we determined the domains and critical amino acids in p27 of …

Viruses infect all cellular life forms and cause various diseases and significant economic
losses worldwide. The majority of viruses are positive-sense RNA viruses. A common …