Actin participates in several essential processes in the cell nucleus. Even though the
presence of actin in the nucleus was proposed more than 30 years ago, nuclear processes …

Actin is a highly conserved protein and one of the major components of the cytoplasm and
the nucleus in eukaryotic cells. In the nucleus, actin is involved in a variety of nuclear …

The abundant cytoskeletal protein actin has numerous cytoplasmic roles. Although there are
many reports of the presence of actin in the nucleus, in general they have been discounted …

Scepticism regarding the existence of actin in the nucleus is finally giving way to the
productive investigation of its functional roles. The identification of actin in several nuclear …

Extensive research in the past decade has significantly broadened our view about the role
actin plays in the life of the cell and added novel aspects to actin research. One of these new …

While actin was discovered in the nucleus over 50 years ago, research lagged for decades
due to strong skepticism. The revitalization of research into nuclear actin occurred after it …

Highlights•Nuclear actin exists in both monomeric and polymeric forms.•Actin monomers
have been mainly linked to regulation of gene expression.•Polymerized nuclear actin …

Although best known from its functions in the cytoplasm, actin also localizes to the cell
nucleus, where it has been linked to many essential functions from regulation of gene …

Actin is a key player for nuclear structure and function regulating both chromosome
organization and gene activity. In the cell nucleus actin interacts with many different proteins …

Cell biological functions of actin have recently expanded from cytoplasm to nucleus, with
actin implicated in such diverse processes as gene expression, transcription factor …