The aim of this study was to investigate the extent of cortical and subcortical lesions in
amyotrophic lateral sclerosis (ALS) using, in combination, voxel based diffusion tensor …

Background Amyotrophic lateral sclerosis (ALS) is characterized by pronounced clinical
heterogeneity in terms of onset and disease progression. Widespread changes in white …

ABSTRACT PURPOSE To assess the involvement of basal ganglia and thalamus in patients
with amyotrophic lateral sclerosis (ALS) using diffusion tensor imaging (DTI) method …

BACKGROUND AND PURPOSE: ALS leads to macrostructural (ie, cortical atrophy and
hyperintensities along the corticospinal tract) and microstructural (ie, gray matter intrinsic …

Studies involving diffusion tensor imaging (DTI) of amyotrophic lateral sclerosis (ALS) with
whole-brain voxel-based analysis yielded variable findings. A systematic review was …

Objective Damage to the cerebral tissue structural connectivity associated with amyotrophic
lateral sclerosis (ALS), which extends beyond the motor pathways, can be visualised by …

BACKGROUND AND PURPOSE: Diffusion tensor imaging (DTI) allows direct visualization
and volumetric analysis of the corticospinal tract (CST). The purpose of this study was to …

Background: Histopathological studies of amyotrophic lateral sclerosis (ALS) are of end
stage disease. Diffusion tensor imaging (DTI) provides the opportunity to investigate …

OBJECTIVE: Aim of present study was to evaluate changes in diffusion tensor imaging (DTI)
parameters in the whole brain of 28 patients with amyotrophic lateral sclerosis (ALS) …

Whether longitudinal diffusion tensor MRI imaging (DTI) can capture disease progression in
patients with amyotrophic lateral sclerosis (ALS) is unclear. The primary goal of this study …