Cytokine patterns in tuberculous and sarcoid granulomas: correlations with histopathologic features of the granulomatous response.

A Bergeron, M Bonay, M Kambouchner… - … (Baltimore, Md.: 1950 …, 1997 - journals.aai.org
Cytokines play an important role in granuloma formation, but the extent that cytokine profiles
are similar in different granulomatous diseases and whether differences in the …

Production of cytokines in sarcoid lymph nodes: preferential expression of interleukin-1β and interferon-γ genes

O Devergne, D Emilie, M Peuchmaur, MC Crevon… - Human pathology, 1992 - Elsevier
Sarcoidosis is a chronic granulomatous disease that may be considered to be a human
model for the delayed-type hypersensitivity reaction. The expression of cytokine genes in …

Cellular composition of hypersensitivity-type granulomas: immunohistochemical analysis of tuberculous and sarcoidal lymphadenitis

C De Wolf-peeters, F Facchetti, VJ Desmet - Human pathology, 1984 - Elsevier
In four cases of sarcoidal and five cases of tuberculous lymphadenitis, the cellular
composition of hypersensitivity-type granulomas was investigated by the application of …

Distribution of IFN‐γ, IL‐4 and TNF‐α protein and CD8 T cells producing IL‐12p40 mRNA in human lung tuberculous granulomas

G Fenhalls, L Stevens, J Bezuidenhout… - …, 2002 - Wiley Online Library
In order to examine the immune response at the site of pathology in tuberculosis, we
analysed cytokines present in lung granulomas, their associations with each other and with …

Detection of endogenous cytokines in sera or in lymph nodes obtained from patients with sarcoidosis

M Asano, T Minagawa, M Ohmichi… - Clinical & Experimental …, 1991 - Wiley Online Library
To investigate the possible role of endogenous cytokines in the immunopathogenesis of
sarcoidosis, a study of cytokines in lymph nodes obtained from patients with active …

In situ production of gamma interferon, interleukin-4, and tumor necrosis factor alpha mRNA in human lung tuberculous granulomas

G Fenhalls, A Wong, J Bezuidenhout… - Infection and …, 2000 - Am Soc Microbiol
Human tuberculous granulomas from five adults undergoing surgery for hemoptysis were
analyzed by nonradioactive in situ hybridization for tumor necrosis factor alpha (TNF-α) …

An in vitro model of the leukocyte interactions associated with granuloma formation in Mycobacterium tuberculosis infection

KA Birkness, J Guarner, SB Sable… - Immunology and cell …, 2007 - Wiley Online Library
The principal defense of the human host against a Mycobacterium tuberculosis infection is
the formation of granulomas, organized collections of activated macrophages, including …

Microdissection of the cytokine milieu of pulmonary granulomas from tuberculous guinea pigs

LH Ly, MI Russell, DN McMurray - Cellular microbiology, 2007 - Wiley Online Library
Summary Levels of IL‐12p40, TNFα, TGFβ, IFNγ and IL‐10 mRNA were assessed by laser
capture microdissection followed by quantitative real‐time PCR in the pulmonary …

Cytokines in sarcoidosis.

C Agostini, G Semenzato - Seminars in respiratory infections, 1998 - europepmc.org
Although the cause of sarcoidosis is still unknown, the combination of the characteristic
morphologic aspect and the immunohistologic pattern of the sarcoid granulomatous lesions …

Lymphocyte subsets in granulomas of human tuberculosis: an in situ immunofluorescence study using monoclonal antibodies

PS Randhawa - Pathology, 1990 - Elsevier
The immunophenotypic characteristics of lymphocyte sub-populations in tissue lesions of
human tuberculosis were investigated in 18 cases. Frozen sections of affected cervical …