Pelvic organ prolapse is characterized as the descent of the pelvic organs into the vaginal
canal. In the USA, there is a 12% lifetime risk for requiring surgical intervention. Although …

Smooth muscle fibers within the vagina, as well as the nerve fibers that contribute to their
control mechanisms, are important for the maintenance and alteration of vaginal length and …

Smooth muscle cells contribute to the mechanical function of various soft tissues, however,
their contribution to the viscoelastic response when subjected to multiaxial loading remains …

Pelvic floor disorders such as pelvic organ prolapse, urinary incontinence, and fecal
incontinence affect a large number of women each year. The pelvic floor can be thought of …

Contractility of the proximal and distal vaginal wall smooth muscle may play distinct roles in
the female sexual response and pelvic support. The goal of this study was to determine …

The objective of this study was to define the regional differences in rat vaginal smooth
muscle contractility and morphology. We evaluated circumferential segments from the …

Introduction Ovarian hormones have an important role in age‐related genital arousal
disorders; however, our knowledge regarding possible vaginal wall morphology and …

The aim of this study was to compare the contractility of the anterior vaginal muscularis
(AVM) from women with and without pelvic organ prolapse (POP). In vitro experiments were …

Ideal animal models are needed to reflect the changes in the biochemical and
biomechanical properties of the vagina that occur in pelvic organ prolapse (POP). In this …

Introduction and hypothesis The aim of the study was to correlate histological and
biomechanical characteristics of the vaginal wall in women with pelvic organ prolapse …