Intron specific polymorphic site of vaspin gene along with vaspin circulatory levels can influence pathophysiology of type 2 diabetes

N Rathwa, N Parmar, SP Palit, R Patel… - Life sciences, 2020 - Elsevier
Vaspin, an insulin-sensitizing adipokine, has been associated with type 2 diabetes (T2D).
The present study aimed to investigate the distribution of genotypes and high-risk alleles of …

[HTML][HTML] Association of vaspin rs2236242 gene polymorphism with serum vaspin level, insulin resistance and diabetes in an Iranian diabetic/pre-diabetic population

M Hosseini, M Nezhadali… - Journal of Medical …, 2021 - ncbi.nlm.nih.gov
Background In recent years, the role of vaspin as an insulin-sensitizer has been studied
widely. This is the investigation that examined the association of vaspin polymorphism …

Association of vaspin rs2236242 gene polymorphism with overweight and obesity in Iranian women.

A Zarei, L Kohan, S Fallahi - 2014 - cabidigitallibrary.org
Introduction: Globally, the incidence of obesity is rising rapidly, not only in industrialized
nations but also in developing countries consistent with which higher vaspin serum …

Obesity risk prediction among women of Upper Egypt: The impact of serum vaspin and vaspin rs2236242 gene polymorphism

SMA Ghany, AA Sayed, SEM El-Deek, HM ElBadre… - Gene, 2017 - Elsevier
Background Vaspin is an adipokine that is potentially linking obesity, insulin resistance,
metabolic syndrome and type-2 diabetes. Aim The present study aimed to investigate the …

Association of vaspin rs2236242 gene variants with type 2 diabetes and obesity in a Chinese population: A prospective, single‐center study

J Li, Q Li, YC Zhu, YK Wang, CP Gao… - Journal of cellular …, 2019 - Wiley Online Library
Aim Vaspin is an adipokine separated from visceral fat tissues of obese diabetic rats. This
study was to investigate the association between vaspin rs2236242 gene polymorphism and …

Genetic variation in the vaspin gene affects circulating serum vaspin concentrations

J Breitfeld, A Tönjes, Y Böttcher, D Schleinitz… - International Journal of …, 2013 - nature.com
Objective: Visceral adipose tissue-derived serine protease inhibitor (vaspin) is an adipokine
potentially linking obesity, insulin resistance and type 2 diabetes. Here, we searched for …

Vaspin gene expression in human adipose tissue: association with obesity and type 2 diabetes

N Klöting, J Berndt, S Kralisch, P Kovacs… - Biochemical and …, 2006 - Elsevier
Recently, vaspin was identified as an adipokine with insulin-sensitizing effects, which is
predominantly secreted from visceral adipose tissue in a rat model of type 2 diabetes. In this …

Association of vaspin rs2236242 with type 2 diabetes mellitus and obesity: a meta-analysis of case-control studies

SM Zain, YF Pung, R Mohamed - Journal of Diabetes & Metabolic …, 2023 - Springer
Background Elevated circulating vaspin levels is linked with type 2 diabetes mellitus (T2DM)
and obesity. The genetic basis of the association between vaspin rs2236242 and T2DM and …

Association of vaspin rs2236242 gene variants and circulating serum vaspin concentrations with coronary artery disease in a Turkish population

R Akcılar, G Yümün, Z Bayat… - Journal of cellular …, 2021 - Wiley Online Library
Coronary artery disease (CAD) is the primary cause of death worldwide. Vaspin was a
recently described adipokine, playing a protective role in many metabolic and …

[PDF][PDF] Vaspin concentration in obesity, impaired glucose tolerance and type 2 diabetes in Egypt

HB Atya, ZA Hassan, AI Amin, SAE Ali - Adv Res Biol Sci, 2013 - researchgate.net
Vaspin is an adipokines with insulin sensitizing effect. The regulation of serum vaspin levels
in humans with obesity and T2DM is still unclear. Investigate the circulating level of vaspin in …