Knowledge of both the global chromatin structure and the gene expression programs of
human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) should …

Identification of molecular components that define a pluripotent human embryonic stem cell
(hESC) provides the basis for understanding the molecular mechanisms regulating the …

Many studies have compared the genetic and epigenetic profiles of human induced
pluripotent stem cells (hiPSCs) to human embryonic stem cells (hESCs) and yet the picture …

Pluripotent embryonic stem cells (ESCs) are considered to have open and accessible
chromatin relative to differentiated cells. However, as many studies supporting these …

Human embryonic stem cells (hESCs) expressing pluripotency markers are assumed to
possess equipotent developmental potential. However, disparate responses to …

Induced pluripotent stem cells (iPSCs) outwardly appear to be indistinguishable from
embryonic stem cells (ESCs). A study of gene expression profiles of mouse and human …

Pluripotency, the ability of a cell to differentiate and give rise to all embryonic lineages,
defines a small number of mammalian cell types such as embryonic stem (ES) cells. While it …

In search of the mechanisms that govern pluripotency and embryonic stem cell (ESC) self-
renewal, a growing list of evidence highlights chromatin as a leading factor, controlling ESC …

Pluripotent stem cells, which include embryonic stem cells and induced pluripotent stem
cells, use a complex network of genetic and epigenetic pathways to maintain a delicate …

The molecular mechanisms underlying pluripotency and lineage specification from
embryonic stem cells (ESCs) are still largely unclear. To address the role of chromatin …