Connexin-based channels contribute to metabolic pathways in the oligodendroglial lineage
Oligodendrocyte precursor cells (OPCs) undergo a series of energy-consuming
developmental events; however, the uptake and trafficking pathways for their energy …
developmental events; however, the uptake and trafficking pathways for their energy …
Connexin-mediated functional and metabolic coupling between astrocytes and neurons
LC Mayorquin, AV Rodriguez, JJ Sutachan… - Frontiers in molecular …, 2018 - frontiersin.org
The central nervous system (CNS) requires sophisticated regulation of neuronal activity.
This modulation is partly accomplished by non-neuronal cells, characterized by the …
This modulation is partly accomplished by non-neuronal cells, characterized by the …
Connexin-dependent neuroglial networking as a new therapeutic target
Astrocytes and neurons dynamically interact during physiological processes, and it is now
widely accepted that they are both organized in plastic and tightly regulated networks …
widely accepted that they are both organized in plastic and tightly regulated networks …
Astroglial metabolic networks sustain hippocampal synaptic transmission
N Rouach, A Koulakoff, V Abudara, K Willecke… - science, 2008 - science.org
Astrocytes provide metabolic substrates to neurons in an activity-dependent manner.
However, the molecular mechanisms involved in this function, as well as its role in synaptic …
However, the molecular mechanisms involved in this function, as well as its role in synaptic …
Connexin and pannexin-based channels in oligodendrocytes: implications in brain health and disease
Oligodendrocytes are the myelin forming cells in the central nervous system (CNS). In
addition to this main physiological function, these cells play key roles by providing energy …
addition to this main physiological function, these cells play key roles by providing energy …
Hypothalamic astroglial connexins are required for brain glucose sensing-induced insulin secretion
Hypothalamic glucose detection participates in maintaining glycemic balance, food intake,
and thermogenesis. Although hypothalamic neurons are the executive cells involved in …
and thermogenesis. Although hypothalamic neurons are the executive cells involved in …
Inhibition of astrocyte connexin 43 channels facilitates the differentiation of oligodendrocyte precursor cells under hypoxic conditions in vitro
Q Wang, Z Wang, Y Tian, H Zhang, Y Fang… - Journal of Molecular …, 2018 - Springer
Oligodendrocyte precursor cells (OPCs) proliferation and differentiation are essential for
remyelination after white matter injury. Astrocytes could promote oligodendrogenesis after …
remyelination after white matter injury. Astrocytes could promote oligodendrogenesis after …
A specific GABAergic synapse onto oligodendrocyte precursors does not regulate cortical oligodendrogenesis
M Balia, N Benamer, MC Angulo - Glia, 2017 - Wiley Online Library
In the brain, neurons establish bona fide synapses onto oligodendrocyte precursor cells
(OPCs), but the function of these neuron‐glia synapses remains unresolved. A leading …
(OPCs), but the function of these neuron‐glia synapses remains unresolved. A leading …
[HTML][HTML] Astrocytes and oligodendrocytes in the thalamus jointly maintain synaptic activity by supplying metabolites
C Philippot, S Griemsmann, R Jabs, G Seifert… - Cell Reports, 2021 - cell.com
Thalamic astrocytes and oligodendrocytes are coupled via gap junctions and form panglial
networks. Here, we show that these networks have a key role in energy supply of neurons …
networks. Here, we show that these networks have a key role in energy supply of neurons …
Adapting brain metabolism to myelination and long‐range signal transduction
J Hirrlinger, KA Nave - Glia, 2014 - Wiley Online Library
In the mammalian brain, the subcortical white matter comprises long‐range axonal
projections and their associated glial cells. Here, astrocytes and oligodendrocytes serve …
projections and their associated glial cells. Here, astrocytes and oligodendrocytes serve …