Mutations of human leucine-rich glioma inactivated (LGI1) gene encoding the epitempin
protein cause autosomal dominant temporal lateral epilepsy (ADTLE), a rare familial partial …

Autosomal dominant lateral temporal epilepsy (ADTLE) is a focal epilepsy syndrome caused
by mutations in the LGI1 gene, which encodes a secreted protein. Most ADLTE-causing …

Mutations in the LGI1/Epitempin gene cause autosomal dominant lateral temporal lobe
epilepsy (ADLTE), a partial epilepsy characterized by the presence of auditory seizures …

Recent studies suggest that mutations in the LGI1/Epitempin gene cause autosomal
dominant lateral temporal epilepsy. This gene encodes a protein of unknown function, which …

Mutations in the LGI1 (leucine-rich, glioma inactivated 1) gene are found in less than a half
of the families with autosomal dominant lateral temporal epilepsy (ADLTE), suggesting that …

Leucine-rich glioma inactivated 3 (LGI3) is a member of LGI/epitempin family of which the
first member, LGI1/epitempin, was shown to be mutated in glioma and autosomal dominant …

Background Autosomal dominant lateral temporal epilepsy (ADLTE) is an inherited
syndrome caused by mutations in the leucine-rich glioma inactivated 1 (LGI1) gene. It is …

Autosomal dominant lateral temporal epilepsy (EPT; OMIM 600512) is a form of epilepsy
characterized by partial seizures, usually preceded by auditory signs. The gene for this …

Mutations in the LGI1 gene are linked to autosomal dominant lateral temporal epilepsy
(ADTLE) in about half of the families tested, suggesting that ADLTE is genetically …

Purpose: To describe the clinical and genetic findings of seven additional pedigrees with
autosomal dominant lateral temporal epilepsy (ADLTE). Methods: A personal and family …