[HTML][HTML] Expression of toll-like receptor 4 contributes to corneal inflammation in experimental dry eye disease

HS Lee, T Hattori, EY Park… - … & visual science, 2012 - iovs.arvojournals.org
Purpose.: To investigate the corneal expression of toll-like receptor (TLR) 4 and determine
its contribution to the immunopathogenesis of dry eye disease (DED). Methods.: Seven to 8 …

[HTML][HTML] Toll-like receptor expression and activation in mice with experimental dry eye

RL Redfern, N Patel, S Hanlon… - … & visual science, 2013 - iovs.arvojournals.org
Purpose.: To investigate the expression and/or function of toll-like receptors (TLRs) and
antimicrobial peptides (AMPs) in dry eye inflammation. Methods.: Experimental dry eye …

Dry eye modulates the expression of toll-like receptors on the ocular surface

RL Redfern, S Barabino, J Baxter, C Lema… - Experimental eye …, 2015 - Elsevier
We aimed to determine if toll-like receptor (TLR) expression is modulated in response to dry
eye-associated conditions and in dry eye syndrome (DES). Primary human corneal …

[HTML][HTML] Inflammatory response to lipopolysaccharide on the ocular surface in a murine dry eye model

KT Simmons, Y Xiao, SC Pflugfelder… - … ophthalmology & visual …, 2016 - arvojournals.org
Purpose: Toll-like receptor 4 (TLR4) alerts cells to the presence of bacteria by initiating an
inflammatory response. We hypothesize that disruption of the ocular surface barrier in dry …

[HTML][HTML] Activation of toll-like receptor (TLR) 2, TLR4, and TLR9 in the mammalian cornea induces MyD88-dependent corneal inflammation

AC Johnson, FP Heinzel, E Diaconu… - … & visual science, 2005 - iovs.arvojournals.org
purpose. Toll-like receptors (TLRs), which recognize microbial products, have an important
role in the host innate immune response. The purpose of the present study was to determine …

[HTML][HTML] Expression and activation of toll-like receptor 3 and toll-like receptor 4 on human corneal epithelial and conjunctival fibroblasts

N Erdinest, G Aviel, E Moallem, I Anteby… - Journal of …, 2014 - Springer
Abstract Background Toll-like receptors (TLRs) are recognized as important contributors to
the initiation and modulation of the inflammatory response in the eye. This study investigated …

[HTML][HTML] The role of toll-like receptor 4 in corneal epithelial wound healing

M Eslani, A Movahedan… - … & visual science, 2014 - iovs.arvojournals.org
Purpose.: We evaluated the role of Toll-like receptor 4 (TLR4) in corneal epithelial wound
healing. Methods.: The expression of TLR4 during in vivo corneal epithelial wound healing …

[HTML][HTML] Hypoxia-altered signaling pathways of toll-like receptor 4 (TLR4) in human corneal epithelial cells

Y Hara, A Shiraishi, Y Ohashi - Molecular vision, 2009 - ncbi.nlm.nih.gov
Purpose Toll-like receptor 4 (TLR4), a member of the TLR family, is an important pattern
recognition molecule that plays a role in the host's innate immune responses to …

[HTML][HTML] MyD88 deficiency protects against dry eye–induced damage

RY Reins, C Lema, J Courson… - … & visual science, 2018 - tvst.arvojournals.org
Purpose: Dry eye disease (DED) is a multifactorial disease associated with ocular surface
inflammation. Toll-like receptors (TLRs) are integral in the initiation of inflammatory …

[HTML][HTML] Expression and function of toll-like receptor-3 and-9 in human corneal myofibroblasts

N Ebihara, S Yamagami, L Chen… - … & visual science, 2007 - iovs.arvojournals.org
purpose. To investigate the expression and function of toll-like receptor (TLR)-3 and-9 in
corneal myofibroblasts. methods. Two types of human keratocytes were used, which were …