MicroRNAs regulating renin–angiotensin–aldosterone system, sympathetic nervous system and left ventricular hypertrophy in systemic arterial hypertension
AC Improta-Caria, MG Aras, L Nascimento… - biomolecules, 2021 - mdpi.com
MicroRNAs are small non-coding RNAs that regulate gene and protein expression.
MicroRNAs also regulate several cellular processes such as proliferation, differentiation, cell …
MicroRNAs also regulate several cellular processes such as proliferation, differentiation, cell …
MicroRNAs in hypertension: mechanisms and therapeutic targets
Hypertension is a complex, multifactorial disease, and its development is determined by a
combination of genetic susceptibility and environmental factors. Several mechanisms have …
combination of genetic susceptibility and environmental factors. Several mechanisms have …
Regulatory mechanisms in arterial hypertension: role of microRNA in pathophysiology and therapy
D Klimczak, K Jazdzewski, M Kuch - Blood pressure, 2017 - Taylor & Francis
Multiple factors underlie the pathophysiology of hypertension, involving endothelial
dysregulation, vascular smooth muscle dysfunction, increased oxidative stress, sympathetic …
dysregulation, vascular smooth muscle dysfunction, increased oxidative stress, sympathetic …
MicroRNAs are involved in end-organ damage during hypertension
WA Heggermont, S Heymans - Hypertension, 2012 - Am Heart Assoc
Even in the new millennium, arterial hypertension remains a serious condition, with
considerable morbidity and mortality worldwide. Crucial in managing the disease is not only …
considerable morbidity and mortality worldwide. Crucial in managing the disease is not only …
Circulating microRNAs and hypertension—from new insights into blood pressure regulation to biomarkers of cardiovascular risk
SPR Romaine, FJ Charchar, NJ Samani… - Current opinion in …, 2016 - Elsevier
Highlights•MicroRNAs have highlighted new regulatory aspects of blood pressure
control.•Array-based studies identified many microRNAs that are dysregulated in …
control.•Array-based studies identified many microRNAs that are dysregulated in …
MicroRNAs in arterial hypertension.
A Synetos, K Toutouzas, K Stathogiannis… - Current topics in …, 2013 - europepmc.org
Arterial hypertension is an epidemic currently affecting almost a billion people worldwide.
The consequences from high blood pressure vary, from peripheral arterial disease and …
The consequences from high blood pressure vary, from peripheral arterial disease and …
Mechanisms and therapeutic potential of microRNAs in hypertension
Highlights•Hypertension is a major risk factor for cardiovascular and renal
disease.•MicroRNAs are important in the pathogenesis of hypertension.•MicroRNAs provide …
disease.•MicroRNAs are important in the pathogenesis of hypertension.•MicroRNAs provide …
MicroRNAs and the heart: small things do matter
N Papoutsidakis, S Deftereos, A Kaoukis… - Current Topics in …, 2013 - ingentaconnect.com
MicroRNAs are small RNA molecules and constitute a relatively novel class of gene
expression regulators, found in the great majority of eukaryotic cells. Their role in human …
expression regulators, found in the great majority of eukaryotic cells. Their role in human …
Role of microRNA in endothelial dysfunction and hypertension
M Nemecz, N Alexandru, G Tanko… - Current hypertension …, 2016 - Springer
Abstract Purpose of Review Hypertension is either a cause or a consequence of the
endothelial dysfunction and a major risk factor for cardiovascular disease (CVD). In vitro and …
endothelial dysfunction and a major risk factor for cardiovascular disease (CVD). In vitro and …
[HTML][HTML] The role of renin-angiotensin aldosterone system related micro-ribonucleic acids in hypertension
HB Wang, J Yang - Saudi Medical Journal, 2015 - ncbi.nlm.nih.gov
Micro-ribonucleic acids (miRNAs) are small (21-25 nucleotide) single-stranded,
evolutionarily conserved non-protein-coding RNAs, which control diverse cellular functions …
evolutionarily conserved non-protein-coding RNAs, which control diverse cellular functions …