Background: Almost one-third of patients with major depressive disorder (MDD) do not
respond to conventional antidepressants, and new treatments for MDD are urgently needed …

Background Major depressive disorder is the second leading cause of years lost to disability
worldwide. Anyu Peibo Capsule has been shown to be effective and safe in phase II trials …

Objective: To evaluate the efficacy and safety of Morinda officinalis oligosaccharide (MOO)
capsules for depressive disorder. Methods: Eight electronic databases were searched for …

OBJECTIVE: To assess the efficacy and safety of Jiawei Xiaoyao (JWXY) capsules on mild
to moderate depression with anxiety symptoms, a randomized, double-blind, double-dummy …

Background Bangpungtongsung-san (BTS) is a representative herbal medicine that has
been widely used for patients with obesity in east Asian countries. Various preclinical …

Objective: Altered glutamatergic neurotransmission has been implicated in the pathogenesis
of depression. This trial evaluated the efficacy and safety of AXS-05 (dextromethorphan …

Objectives: Shuganjieyu capsule is a pure herbal pharmaceutical product for depression.
Our objective was to explore the effectiveness and safety of Shuganjieyu capsule for the …

Objectives With existing therapies for major depressive disorder (MDD), improvements in
functioning and quality of life, often trail behind depressive symptom improvement. AXS-05 …

BACKGROUND: Evaluate the efficacy and tolerability of extended release quetiapine
fumarate (quetiapine XR) once-daily monotherapy for patients with major depressive …

Abstract Buprenorphine/samidorphan (BUP/SAM; ALKS 5461) is an investigational opioid
system modulator for the adjunctive treatment of patients with major depressive disorder …