To investigate the effect of resting blood oxygen concentration on the hemodynamic
response to functional brain activation, we compared activation-induced changes in …

The dynamic changes in cerebral metabolic rate of oxygen (CMRO 2) and oxygen supply
during brain functions have not been well-characterized. To examine this issue, experiments …

Recently, a universal, simple, and fail-safe mechanism has been proposed by which
cerebral blood flow (CBF) might be coupled to oxygen metabolism during neuronal …

We observed changes in the local cerebral blood flow (LCBF), red blood cell (RBC)
concentration and RBC velocity in α-chloralose anesthetized rats using laser-Doppler …

In order to study the effect of hypoxic hypoxia upon regional cerebral metabolism and blood
flow the arterial Poa of lightly anaesthetized rats was lowered to about 35, 29 and 23 mm …

Prolonged exposure to low oxygen environments provokes systemic adaptations that result
in maintained oxygen delivery to the brain, and central cerebrovascular and metabolic …

Cerebral hemodynamic response to acute hyperoxia was investigated in awake mice. Using
laser-Doppler flowmetry (LDF), baseline cerebral blood flow (CBF) and the cerebrovascular …

The relationship between measurements of cerebral blood oxygenation and neuronal
activity is highly complex and depends on both neurovascular and neurometabolic …

Polarigraphic microelectrodes were used to study the distribution of oxygen tension (pO 2) in
arterioles (lumen diameters 8–80 µm) and venules (lumen diameters 8–120 µm) in the rat …

The dynamic changes in local hemoglobin concentration and oxygenation in the cerebral
cortex closely correlate with neuronal activity through the changes of cerebral metabolism …