Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease with progressive fibrosis and
death within 2–3 y of diagnosis. IPF incidence and prevalence rates are increasing annually …

Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease where invasive
pulmonary myofibroblasts secrete collagen and destroy lung integrity. Here, we show that …

Severe forms of idiopathic interstitial pneumonia (IIP), such as usual interstitial pneumonia
(UIP), can be impervious to modern steroid and immunosuppressive treatment regimens …

The aberrant fibrotic and repair responses in the lung are major hallmarks of idiopathic
pulmonary fibrosis (IPF). Numerous antifibrotic strategies have been used in the clinic with …

Repetitive pulmonary injury causes fibrosis and inflammation that underlies chronic lung
diseases such as idiopathic pulmonary fibrosis (IPF). Interleukin 11 (IL11) is important for …

Interleukins, a group of cytokines participating in inflammation and immune response, are
proved to be involved in the formation and development of pulmonary fibrosis. In this article …

Increased lung IL-4 expression in pulmonary fibrosis suggests a potential pathogenetic role
for this cytokine. To dissect this role, bleomycin-induced pulmonary inflammation and …

IL-10 is most commonly recognized as an anti-inflammatory cytokine possessing
immunosuppressive effects necessary for regulated resolution of proinflammation. However …

Lung fibrosis is the hallmark of the interstitial lung diseases. Alveolar epithelial cell (AEC)
injury is a key step that contributes to a profibrotic microenvironment. Fibroblasts and …

Idiopathic pulmonary fibrosis (IPF) is a fatal disease that is unresponsive to current therapies
and characterized by excessive collagen deposition and subsequent fibrosis. While …