Negative rumours about a vaginal ring for HIV-1 prevention in sub-Saharan Africa

M Chitukuta, Z Duby, A Katz, T Nakyanzi… - Culture, health & …, 2019 - Taylor & Francis
Rumours may influence health-related behaviours, including the uptake of and adherence to
HIV prevention products. This study assessed the safety and effectiveness of a vaginal ring …

Impact of the dapivirine vaginal ring on sexual experiences and intimate partnerships of women in an HIV prevention clinical trial: managing ring detection and hot sex

ND Laborde, E Pleasants, K Reddy, M Atujuna… - AIDS and Behavior, 2018 - Springer
Vaginally-inserted HIV prevention methods have been reported to impact the sexual
experience for women and their partners, and hence impacts acceptability of and adherence …

Does the ring work? Perceptions and understanding of the efficacy of a dapivirine vaginal ring for HIV prevention amongst women in a placebo-controlled trial

J Etima, AWK Katz, Z Duby, M Garcia… - AIDS and Behavior, 2022 - Springer
As demonstrated by the Phase III clinical trial, MTN-020/ASPIRE, the monthly dapivirine
vaginal ring is well tolerated and reduces the risk of HIV-1 as a woman-initiated prevention …

Men's sexual experiences with the dapivirine vaginal ring in Malawi, South Africa, Uganda and Zimbabwe

ET Montgomery, AWK Katz, Z Duby, LE Mansoor… - AIDS and Behavior, 2021 - Springer
The dapivirine vaginal ring has been well-tolerated and shown to prevent HIV in clinical
trials. The ring is female initiated, yet endorsement for use is sought from male partners in …

Acceptability and use of a dapivirine vaginal ring in a phase III trial

ET Montgomery, A van der Straten, M Chitukuta… - Aids, 2017 - journals.lww.com
Background: The MTN-020/ASPIRE trial evaluated the safety and effectiveness of the
dapivirine vaginal ring for prevention of HIV-1 infection among African women. A nested …

Characteristics of women enrolled into a randomized clinical trial of dapivirine vaginal ring for HIV-1 prevention

T Palanee-Phillips, K Schwartz, ER Brown… - PloS one, 2015 - journals.plos.org
Introduction Women in sub-Saharan Africa are a priority population for evaluation of new
biomedical HIV-1 prevention strategies. Antiretroviral pre-exposure prophylaxis is a …

Efficacy and action of the dapivirine vaginal ring as understood by women participating in an open label extension study

K Naidoo, AWK Katz, G Morgan, R Krishnaveni… - AIDS and Behavior, 2023 - Springer
The concept of efficacy, and how HIV prevention products biologically work can be complex.
We report on women's interpretation of efficacy of the dapivirine vaginal ring and how they …

Safety and efficacy of a dapivirine vaginal ring for HIV prevention in women

A Nel, N van Niekerk, S Kapiga… - … England Journal of …, 2016 - Mass Medical Soc
Background The incidence of human immunodeficiency virus (HIV) infection remains high
among women in sub-Saharan Africa. We evaluated the safety and efficacy of extended use …

Safety, adherence, and HIV-1 seroconversion among women using the dapivirine vaginal ring (DREAM): an open-label, extension study

A Nel, N Van Niekerk, B Van Baelen, M Malherbe… - The Lancet …, 2021 - thelancet.com
Summary Background The Ring Study, a phase 3 trial in 1959 sexually active women
(randomised 2: 1), showed a favourable safety profile and a 31% HIV-1 infection risk …

Hygiene, blood flow, and vaginal overload: why women removed an HIV prevention vaginal ring during menstruation in Malawi, South Africa, Uganda and Zimbabwe

Z Duby, AWK Katz, EN Browne, P Mutero, J Etima… - AIDS and behavior, 2020 - Springer
We assessed the interference between vaginal ring use and menses among women who
participated in the qualitative component of the MTN-020/ASPIRE vaginal ring trial in …