Background Vascular calcification is the most prominent underlying pathological finding in
patients with uraemia, and is a predictor of mortality in this population. Fetuin-A (α 2 …

Abstract Background. Fetuin-A (α2-Heremans Schmid glycoprotein) has recently been
identified as a circulating inhibitor of calcification and is regulated as a negative acute phase …

Calcifying atherosclerosis is an active process, which is controlled by calcification inhibitors
and inducers. Fetuin-A, an acute phase glycoprotein, is one of the more powerful circulating …

Low fetuin-A levels are associated with cardiovascular death: Impact of variations in the
gene encoding fetuin. Background Vascular calcification is common among end-stage renal …

Background. Fetuin-A is a serum protein that inhibits ectopic vascular calcification and is
present in lower concentrations in end-stage renal disease than in healthy controls. Whether …

Background: Cardiovascular disease (CVD) is the leading cause of mortality in hemodialysis
(HD). An elevated incidence of cardiovascular calcifications (CVC) is observed in HD. Fetuin …

In past decades, extraosseous (including cardiovascular) calcification was predominantly
regarded as a passive process of limited pathophysiological significance. It was thought that …

Soft-tissue and vascular calcification are highly prevalent in end-stage renal disease
(ESRD). Vascular calcifications manifest as both medial and intimal calcification of arteries …

Fetuin-A is an important inhibitor of extraosseous calcification, but some of the studies that
used ELISAs did not identify a significant relationship between serum fetuin-A levels and …

Reduced serum levels of the calcification inhibitor fetuin-A associate with increased
cardiovascular mortality in dialysis patients. Fetuin-A–deficient mice display calcification of …