The impact of the opioid epidemic on pregnant people and children is a growing public
health crisis. Understanding how opioids affect the developing brain during pregnancy and …

Background Preclinical data demonstrate that opioids modulate brain reward signaling
through an inflammatory cascade, but this relationship has yet to be studied in opioid …

Background The increasing magnitude of the opioid crisis and rising rates of neonatal
abstinence syndrome (NAS) diagnoses highlight the need for increased research into how …

Substance use, specifically the use of prescription and non-prescription opioids among
pregnant women, is a major public health issue and chief contributor to the opioid crisis. The …

The increased incidence of opioid use during pregnancy warrants investigation to reveal the
impact of opioid exposure on the developing fetus. Exposure during critical periods of …

BACKGROUND: Chronic use of opioids is associated with hematologic and immunologic
effects, including lymphopenia. Despite an increase in opioid use during pregnancy, little is …

The rates of opioid use disorder during pregnancy have more than quadrupled in the last
decade, resulting in numerous infants suffering exposure to opioids during the perinatal …

Purpose: The rising issue of opioid use during pregnancy poses an increased risk of fetal
exposure to opioids in-utero and the development of neonatal abstinence syndrome (NAS) …

The impact of prenatal opioids on the developing brain is not well studied, specifically on
white matter tract development shortly after birth [1–3]. Our pilot study aims to evaluate and …