Much of the variation in inherited risk of colorectal cancer (CRC) is probably due to
combinations of common low risk variants. We conducted a genome-wide association study …

To identify colorectal cancer (CRC) susceptibility alleles, we conducted a genome-wide
association study. In phase 1, we genotyped 550,163 tagSNPs in 940 familial colorectal …

In a genome-wide association study to identify loci associated with colorectal cancer (CRC)
risk, we genotyped 555,510 SNPs in 1,012 early-onset Scottish CRC cases and 1,012 …

Using a multistage genetic association approach comprising 7,480 affected individuals and
7,779 controls, we identified markers in chromosomal region 8q24 associated with …

Genome-wide association (GWA) studies have identified multiple loci at which common
variants modestly influence the risk of developing colorectal cancer (CRC). To enhance …

Genetic susceptibility to colorectal cancer is caused by rare pathogenic mutations and
common genetic variants that contribute to familial risk. Here we report the results of a two …

We performed a meta-analysis of five genome-wide association studies to identify common
variants influencing colorectal cancer (CRC) risk comprising 8,682 cases and 9,649 …

Homozygosity for the G allele of rs6983267 at 8q24 increases colorectal cancer (CRC)
risk∼ 1.5 fold. We report here that the risk allele G shows copy number increase during …

Genome-wide association studies (GWAS) have identified ten loci harboring common
variants that influence risk of developing colorectal cancer (CRC). To enhance the power to …

To further dissect the genetic architecture of colorectal cancer (CRC), we performed whole-
genome sequencing of 1,439 cases and 720 controls, imputed discovered sequence …